CAJ | 학술논문

建立了尿液中甲卡西酮类毒品顶空固相微萃取-气相色谱-质谱联用的含量测定方法。在添加定量甲卡西酮类标准品的尿液试样中,加入固体Na2 CO3,以MDMA为内标,调溶液pH10,80℃下加热搅拌,用70μm乙烯二醇-二乙烯基苯共聚物( CW/DVB)萃取头顶空萃取20 min,GC-MS检测,获得良好线性,其标准曲线线性范围在0．06μg~1．86μg·mL-1,最小检测限可达0．01μg·mL-1,平均回收率均在85%~115%之间。相对标准偏差均在11%以内。
건립료뇨액중갑잡서동류독품정공고상미췌취-기상색보-질보련용적함량측정방법。재첨가정량갑잡서동류표준품적뇨액시양중,가입고체Na2 CO3,이MDMA위내표,조용액pH10,80℃하가열교반,용70μm을희이순-이을희기분공취물( CW/DVB)췌취두정공췌취20 min,GC-MS검측,획득량호선성,기표준곡선선성범위재0．06μg~1．86μg·mL-1,최소검측한가체0．01μg·mL-1,평균회수솔균재85%~115%지간。상대표준편차균재11%이내。
A simple method for detection of methcathinones in urine by SPME-GC-MS( SIM) was developed. In the urine sample,the standard solution of methcathinones,solid sodium carbonate and MDMA(internal standard solution)was added. The solution was stirred and heated under 80℃ on the condition of pH10. Then,the sample was extracted by HS-SPME with 70μm ethyleneglycol-vi-nylbenzene copolymer( CW/DVB) ,a middle-polar coated fiber for 20 minutes and then analyzed by GC-MS. The result show good linearity in the range of 0. 06μg~1. 86μg·mL-1 and LOD was 0. 01μg·mL-1. The value of accuracy was varying from 85% ~115% and RSD was within 11%.