CAJ | 학술논문

目的：分析儿童多发性大动脉炎( takayasu arteritis, TA)的临床特征,提高临床对儿童TA的认识。方法对以高血压脑病发病的儿童TA 1例的临床资料进行回顾性分析并复习相关文献。结果本例因发热6 d,头痛、呕吐4 d,阵发性抽搐1 d,以颅内感染收入院。行头颅CT检查未见异常,后发现血压高、尿蛋白,疑似肾疾病及高血压脑病,后因听诊脐周有血管杂音,进一步行腹部彩色多普勒超声及数字减影血管造影检查明确诊断为TA。予醋酸泼尼松及小剂量双嘧达莫治疗后病情很快控制,随访半年无病情活动。结论 TA可侵犯机体多个器官系统,临床表现缺乏特异性,提高对本病的认识,尽早明确诊断并治疗,可改善患儿的预后。
목적：분석인동다발성대동맥염( takayasu arteritis, TA)적림상특정,제고림상대인동TA적인식。방법대이고혈압뇌병발병적인동TA 1례적림상자료진행회고성분석병복습상관문헌。결과본례인발열6 d,두통、구토4 d,진발성추휵1 d,이로내감염수입원。행두로CT검사미견이상,후발현혈압고、뇨단백,의사신질병급고혈압뇌병,후인은진제주유혈관잡음,진일보행복부채색다보륵초성급수자감영혈관조영검사명학진단위TA。여작산발니송급소제량쌍밀체막치료후병정흔쾌공제,수방반년무병정활동。결론 TA가침범궤체다개기관계통,림상표현결핍특이성,제고대본병적인식,진조명학진단병치료,가개선환인적예후。
Objective To analyze the clinical characteristics of Takayasu's arteritis (TA) and to raise the clinical awareness of TA with hypertensive encephalopathy as initial symptom. Methods A retrospective study of one child with TA was performed, and the related literature was reviewed. Results This patient was admitted to hospital and diagnosed with in-tracranial infection for fever for 6 days, headache and vomitting for 4 days, paroxysmal convulsion for 1 day. The head CT scan did not show abnormal findings. Then hypertension and proteinuria were found in this patient. The signs were once con-sidered to be caused by suspected renal disease and hypertensive encephalopathy. This case was diagnosed as TA by thoracic and abdominal Doppler ultrasound after the vascular murmur around the navel was heard. The disease was soon controlled after medication of oral prednisone and low-dose dipyridamole and there was no disease activity after a 6-month follow-up. Conclu-sion TA in children can invade multiple organs and systems. The clinical manifestations are lack of speciality. We should improve the awareness of TA. Early diagnosis and treatment can improve the prognosis of the disease.