CAJ | 학술논문

本文通过回顾脾阳虚证模型的造模方法，将其分为模拟传统中医病因的造模方法和现代医学造模方法。目前尚无公认的脾阳虚证造模方法，且主要存在以下问题：现代医学造模方法不符合中医病因病机的规律；模型动物的阳虚症状评价不确切；某些造模方法同时可致其他病症；脾虚证模型的名称混乱不统一；脾阳虚证和脾气虚证的造模方法难以区别等。脾阳虚证模型的评价指标种类繁多，但国内尚未形成标准的模型评价体系。目前，模型评价主要存在以下不规范之处：模型动物的宏观症状缺乏客观量化的评价指标；缺乏中医特色的舌象、脉象；反证方剂的选择不统一；相似的证候未排除；微观指标混乱不成体系等。本文将就脾阳虚证动物模型作一综述。
본문통과회고비양허증모형적조모방법，장기분위모의전통중의병인적조모방법화현대의학조모방법。목전상무공인적비양허증조모방법，차주요존재이하문제：현대의학조모방법불부합중의병인병궤적규률；모형동물적양허증상평개불학절；모사조모방법동시가치기타병증；비허증모형적명칭혼란불통일；비양허증화비기허증적조모방법난이구별등。비양허증모형적평개지표충류번다，단국내상미형성표준적모형평개체계。목전，모형평개주요존재이하불규범지처：모형동물적굉관증상결핍객관양화적평개지표；결핍중의특색적설상、맥상；반증방제적선택불통일；상사적증후미배제；미관지표혼란불성체계등。본문장취비양허증동물모형작일종술。
The paper was aimed to review the modeling methods of spleen-yang deficiency, which can be classified into imitating traditional Chinese medicine (TCM) etiology methods and modern medicine methods. At present, methods of modeling were not generally accepted and the main presented problems were as follows. Modern medicine methods did not conformed to the rules of TCM etiology and pathogenesis. The evaluation of yang deficiency models was not accurate. Some modeling methods can lead to other diseases at the same time. The names of spleen deficiency model were not unified. It was difficult to distinguish the modeling methods of spleen-yang deficiency and spleen-qi deficiency, and etc. Model evaluation of spleen-yang deficiency was various. However, the domestic standard evaluation system had not been formed. The main model evaluation problems were as follows. Macro symptoms of the model lacked of objective and quantitative evaluation. It lacked of evaluation indexes of pulse and tongue with TCM characteristics. The disproof of prescription selection was not unified. Similar syndromes had not been ruled out. The microscopic indexes were fragmented, and etc. This paper reviewed on animal modeling methods of spleen-yang deficiency.