CAJ | 학술논문

目的：应用文献计量学方法，分析参归方中关键药物参归配比与疾病科属的关系。方法：从中国传统医药古籍中检索出含有参归的49首方剂，并建立数据库，对其药材基源、主治疾病科属和参归配伍比例进行统计分析。结果：49首参归方剂，主要用于治疗内科疾病16次（32.65%）、妇科疾病17（34.69%）次和儿科疾病8次（16.32%），其中“归”全为当归，“参”有3种，人参40次，党参8次，苦参1次；人参-当归二者配比常小于或等于1，党参-当归二者配比常大于1，所治疾病科属以内科和妇科的方剂出现频率最多。结论：运用数据分析方法，能有效发现参归方组方配伍中人参-当归药对的应用特点与规律，为临床用药和新药开发提供理论依据与参考。
목적：응용문헌계량학방법，분석삼귀방중관건약물삼귀배비여질병과속적관계。방법：종중국전통의약고적중검색출함유삼귀적49수방제，병건립수거고，대기약재기원、주치질병과속화삼귀배오비례진행통계분석。결과：49수삼귀방제，주요용우치료내과질병16차（32.65%）、부과질병17（34.69%）차화인과질병8차（16.32%），기중“귀”전위당귀，“삼”유3충，인삼40차，당삼8차，고삼1차；인삼-당귀이자배비상소우혹등우1，당삼-당귀이자배비상대우1，소치질병과속이내과화부과적방제출현빈솔최다。결론：운용수거분석방법，능유효발현삼귀방조방배오중인삼-당귀약대적응용특점여규률，위림상용약화신약개발제공이론의거여삼고。
This study was aimed to explore the relationship between the Shen-Gui-Fang(SGF) formula of different proportions and treatments for diseases with the method of bibliometrics. A total of 49 formulae of SGF from ancient books of traditional Chinese medicine (TCM) were retrieved and the database was established in order to analyze the origin of herbal medicine and the relationship with the ratio of the key medicinal material, as well as the treatment for major diseases. The results showed that 49 SGF formulae were mainly used in the treatment of internal disorders for 16 times (32.65%), gynecological disorders for 17 times (34.69%) and pediatric disorders for 8 times (16.32%). Guistanded forAngelica sinensis. There were 3 types ofShen, which werePanax ginsengfor 40 times,Codonopsis pilosulafor 8 times, andSophora flavescensfor 1 time. The ratio betweenP. ginsengandA. sinensiswas less or equal to 1. The ratio betweenC. pilosulaandA. sinensiswas usually more than 1. The formulae with the highest frequency were in the treatment of internal medicine and gynecological diseases. Statistical analysis was used to find the application features and rules of the combination ofP. ginsengandA. sinensisin SGF formula, in order to provide theoretical evidences and references for clinical medication selection and new medication research.