中国医药指南
中國醫藥指南
중국의약지남
Guide of China Medicine
2015年
26期
31-31,33
,共2页
Her-2%Luminal型乳腺癌%组织病理学
Her-2%Luminal型乳腺癌%組織病理學
Her-2%Luminal형유선암%조직병이학
Her-2%Luminal breast cancer%Expression%Histopathological grade
目的：分析Her-2在Luminal型乳腺癌中表达及组织病理学分级。方法选取我院收治的156例Luminal型乳腺癌患者，采用免疫组织化学法考察Her-2癌基因蛋白在Luminal型乳腺癌中的表达及组织病理学分级。结果 Her-2在Luminal乳腺癌中的总阳性率为46.8%，其表达多见于Paget’s病、导管内癌、浸润性导管癌等，而巨大纤维腺癌、导管内乳头状癌、浸润性小叶癌检测均为阴性。Her-2在Luminal型乳腺癌中的表达与淋巴结转移有显著关系。结论检测Her-2的表达可以为临床制定乳腺癌的综合治疗方法提供有效依据和参考价值。
目的：分析Her-2在Luminal型乳腺癌中錶達及組織病理學分級。方法選取我院收治的156例Luminal型乳腺癌患者，採用免疫組織化學法攷察Her-2癌基因蛋白在Luminal型乳腺癌中的錶達及組織病理學分級。結果 Her-2在Luminal乳腺癌中的總暘性率為46.8%，其錶達多見于Paget’s病、導管內癌、浸潤性導管癌等，而巨大纖維腺癌、導管內乳頭狀癌、浸潤性小葉癌檢測均為陰性。Her-2在Luminal型乳腺癌中的錶達與淋巴結轉移有顯著關繫。結論檢測Her-2的錶達可以為臨床製定乳腺癌的綜閤治療方法提供有效依據和參攷價值。
목적：분석Her-2재Luminal형유선암중표체급조직병이학분급。방법선취아원수치적156례Luminal형유선암환자，채용면역조직화학법고찰Her-2암기인단백재Luminal형유선암중적표체급조직병이학분급。결과 Her-2재Luminal유선암중적총양성솔위46.8%，기표체다견우Paget’s병、도관내암、침윤성도관암등，이거대섬유선암、도관내유두상암、침윤성소협암검측균위음성。Her-2재Luminal형유선암중적표체여림파결전이유현저관계。결론검측Her-2적표체가이위림상제정유선암적종합치료방법제공유효의거화삼고개치。
Objective To investigate the expression and the relationship with histopathological grade of Her-2 in Luminal breast cancer.Methods 156 cases of Luminal breast cancer were selected. Immunohistochemistry was used to investigate the expression and the relationship with histopathological grading of Her-2. Results The total positive rate of Her-2 in Luminal breast cancer was 46.8%, and Her-2 expressed in Paget’s, intraductal carcinoma, invasive ductal carcinoma and so on, Her-2 was not expressed in huge fiber adenocarcinoma, intraductal papilary carcinoma and invasive lobular carcinoma. There is a significant relationship between Her-2 and lymphatic metastasis.Conclusion Detecting Her-2 expression could provide effective basis in formulating the comprehensive treatment of breast cancer.
