CAJ | 학술논문

目的：探讨促排周期中使用戊酸雌二醇（补佳乐）联合复方玄驹胶囊治疗后对患者子宫内膜变化、排卵及受孕率的影响。方法随机将2013年1月～2014年12月我院门诊63例 PCOS 并中医诊断为肾阳虚型排卵障碍患者分为两组，对照组31例为：氯米芬+补佳乐治疗，治疗组32例为：氯米芬+补佳乐+复方玄驹胶囊治疗，观察两组的子宫内膜变化、排卵情况及妊娠率。结果在氯米芬促排卵治疗中，对比单纯加补佳乐治疗，联合使用补佳乐和复方玄驹胶囊后子宫内膜、排卵情况及妊娠率均有所升高，妊娠率高达59.37%。结论对于 PCOS并肾阳虚型排卵障碍患者，在氯米芬促排周期中，若联合使用补佳乐和复方玄驹胶囊，可促进子宫内膜发育，利于胚胎着床，从而提高临床妊娠率，临床疗效显著。
목적：탐토촉배주기중사용무산자이순（보가악）연합복방현구효낭치료후대환자자궁내막변화、배란급수잉솔적영향。방법수궤장2013년1월～2014년12월아원문진63례 PCOS 병중의진단위신양허형배란장애환자분위량조，대조조31례위：록미분+보가악치료，치료조32례위：록미분+보가악+복방현구효낭치료，관찰량조적자궁내막변화、배란정황급임신솔。결과재록미분촉배란치료중，대비단순가보가악치료，연합사용보가악화복방현구효낭후자궁내막、배란정황급임신솔균유소승고，임신솔고체59.37%。결론대우 PCOS병신양허형배란장애환자，재록미분촉배주기중，약연합사용보가악화복방현구효낭，가촉진자궁내막발육，리우배태착상，종이제고림상임신솔，림상료효현저。
Objective To explore the influence of the endometrial variation, the ovulation, and the pregnancy rate on the cycle of ovulation-promoting after of combination of Compound Xuanju Capsule( CXC) and estradiol valerate to dysfunctional infertility( ODI) patients of Shen-yang deficiency syndrome( SYDS). Methods From January 2013 to December 2014 in our hospital outpatient service, 2 groups of 63 cases whose were diagnosed polycystic ovarian syndrome (PCOS) and ovulatory dysfunctional infertility of Shen-yang deficiency in Chinese Medicine, the control group ( 31 cases, treated with clomiphene citrate( CC)+ estradiol valerate), the treatment group ( 32 cases, treated with CC, estradiol valerate and CXC). The post-treatment clinical symptoms, the endometrial variation, the ovulation, and the pregnancy rate, and so on were observed. Results It was better in the treatment group (P<0.05). After treatment better effects on the endometrial variation, the ovulation and the pregnancy rate were obtained in the treatment group, showing statistical difference when compared with the control group (P<0.05), Pregnancy rate is as high as 59.25%. Conclusion Patient whose were diagnosed PCOS and ovulatory dysfunctional infertility of Shen-yang deficiency in Chinese Medicine, treated with CC, estradiol valerate and CXC can promote endometrial development, benefit embryo implantation, thus improve the clinical pregnancy rate,(as high as 59.25%).