CAJ | 학술논문

目的：探讨文拉法辛治疗心力衰竭伴焦虑及抑郁患者的临床疗效。方法选取2012年6月至2013年6月郑州市第九人民医院收治的心力衰竭伴焦虑、抑郁患者90例，按随机数字表法将患者资料分为两组，各45例。对照组患者接受心内科常规治疗，研究组患者在对照组基础上加用文拉法辛治疗，比较两组患者的临床疗效。结果研究组患者总有效率为95.6%，明显高于对照组的80.0%，差异有统计学意义（P＜0.05）；研究组患者HAMD、SAS评分均明显低于对照组，差异均有统计学意义（均P＜0.05）。结论文拉法辛能有效改善心力衰竭患者的焦虑、抑郁状况，提高临床疗效，改善患者的生活质量。
목적：탐토문랍법신치료심력쇠갈반초필급억욱환자적림상료효。방법선취2012년6월지2013년6월정주시제구인민의원수치적심력쇠갈반초필、억욱환자90례，안수궤수자표법장환자자료분위량조，각45례。대조조환자접수심내과상규치료，연구조환자재대조조기출상가용문랍법신치료，비교량조환자적림상료효。결과연구조환자총유효솔위95.6%，명현고우대조조적80.0%，차이유통계학의의（P＜0.05）；연구조환자HAMD、SAS평분균명현저우대조조，차이균유통계학의의（균P＜0.05）。결논문랍법신능유효개선심력쇠갈환자적초필、억욱상황，제고림상료효，개선환자적생활질량。
Objective To investigate the clinical efficacy of venlafaxine in treatment of anxiety and depression in patients with heart failure.Methods From June 2012 to June 2013,90 patients with heart failure accompanied by anxiety and depression in Ninth People's Hospital of Zhengzhou city were divided into two groups according to the random number table method,45 cases in each group.The control group was treated with conventional therapy,and the study group was treated with Vin Rafa Sin on the basis of the control group.The clinical efficacy of the two groups was compared.Results Patients in the study group,total effective rate was 95.6%,significantly higher than that of control group(80.0%),the difference is statisticaly significant(P<0.05);patients in the study group HAMD,SAS score were significantly lower than those of the control group,differences were statisticaly significant(P<0.05).Conclusion Venlafaxine can effectively improve heart failure patients with anxiety and depression,improve the clinical efficacy,comprehensively improve the quality of life of the patients.