CAJ | 학술논문

目的：通过研究帕金森病患者结肠运输时间、直肠感觉及模拟排便功能，探讨帕金森病患者便秘产生原因。方法：通过对2010年1月－2015年3月于本院神经内科住院的68例帕金森病患者服用不透X线标记物追踪法测定结肠运输时间，气囊法测定直肠感觉，模拟排便测定直肠排空功能。同期在本院体检中心随机抽取同年龄段无便秘健康志愿者50例作为对照。结果：帕金森病患者结肠运输时间延长比例较对照组高（46／68 VS 2／50）（P＜0．05）。帕金森病患者直肠初始感觉容积为（39．71±8．92）m l高于对照组的（28．80±4．22）m l （ P＜0．05），帕金森病患者初始便意感觉容积为（83．09±8．97）ml高于对照组的（70．00±5．20）ml（P＜0．05）。帕金森病患者直肠排空率为（48．01±18.81）％低于对照组的（83．88±12．70）％（ P＜0．05）。结论：帕金森病患者存在结肠运输功能下降、直肠感觉异常及直肠排空率下降。
목적：통과연구파금삼병환자결장운수시간、직장감각급모의배편공능，탐토파금삼병환자편비산생원인。방법：통과대2010년1월－2015년3월우본원신경내과주원적68례파금삼병환자복용불투X선표기물추종법측정결장운수시간，기낭법측정직장감각，모의배편측정직장배공공능。동기재본원체검중심수궤추취동년령단무편비건강지원자50례작위대조。결과：파금삼병환자결장운수시간연장비례교대조조고（46／68 VS 2／50）（P＜0．05）。파금삼병환자직장초시감각용적위（39．71±8．92）m l고우대조조적（28．80±4．22）m l （ P＜0．05），파금삼병환자초시편의감각용적위（83．09±8．97）ml고우대조조적（70．00±5．20）ml（P＜0．05）。파금삼병환자직장배공솔위（48．01±18.81）％저우대조조적（83．88±12．70）％（ P＜0．05）。결론：파금삼병환자존재결장운수공능하강、직장감각이상급직장배공솔하강。
Objective :To explore the causes of the Parkinson’s sufferers constipation ,by observing the colonic transit time ,rectal sensation and simulate the defecation function of Parkinson’s disease(PD) .Methods :The data of 68 consti‐pation patients with PD were selected from January 2010 to March 2015 in neurology department ,which were com‐pared with 50 normal controls .Results:The colonic transit time of Parkinson’s sufferers (46/68 VS 2/50) ,rectum ini‐tial feeling volume (39 .71 ± 8 .92)ml and rectum original meaning feeling volume (83 .09 ± 8 .97)ml all were higher than the control group (P<0 .05) .The rectum emptying rate (48 .01 ± 18 .81)% was lower than the control group (83 .88 ± 12 .70)% (P<0 .05) .Conclusion:Parkinson’s disease colon transit function ,rectal feeling and rectal emptying rate all w as decline .