医学信息
醫學信息
의학신식
Medical Information
2015年
35期
84-84
,共1页
结直肠癌%病原菌
結直腸癌%病原菌
결직장암%병원균
Colorectal cancer%Pathogen
目的：观察结直肠癌患者经过化疗后感染病原菌的分布并分析其影响因素。方法选取我院于2013年3月~2015年2月收治的260例结直肠癌患者，采集患者伤口分泌物作为标本并行细菌培养，对病原菌进行鉴定，并对其他可能影响病原菌分布的因素进行分析。结果入选的260例患者中有62例出现化疗后感染(23.85%)，第1次化疗后感染的患者数为28例，第2次化疗后感染的患者数为34例。主要发生感染部位为呼吸道感染33例，消化道感染10例，皮肤及附件感染5例，泌尿道感染9例，其余部位感染5例。进行细菌学分析检出结果见革兰阴性菌占69.35%(43/62)，革兰阳性菌占22.58%(14/62)，所占比例最大的是大肠埃希菌与铜绿假单胞菌(分别为25.81%和14.52%)，手术切口也发生感染，主要受患者体重指数、Dukes分期、是否合并糖尿病及手术类别有关。结论肥胖、是否患有糖尿病及癌症分期等影响结直肠癌患者化疗后感染，以革兰阴性杆菌为主。医院有责任采取措施预防感染。
目的：觀察結直腸癌患者經過化療後感染病原菌的分佈併分析其影響因素。方法選取我院于2013年3月~2015年2月收治的260例結直腸癌患者，採集患者傷口分泌物作為標本併行細菌培養，對病原菌進行鑒定，併對其他可能影響病原菌分佈的因素進行分析。結果入選的260例患者中有62例齣現化療後感染(23.85%)，第1次化療後感染的患者數為28例，第2次化療後感染的患者數為34例。主要髮生感染部位為呼吸道感染33例，消化道感染10例，皮膚及附件感染5例，泌尿道感染9例，其餘部位感染5例。進行細菌學分析檢齣結果見革蘭陰性菌佔69.35%(43/62)，革蘭暘性菌佔22.58%(14/62)，所佔比例最大的是大腸埃希菌與銅綠假單胞菌(分彆為25.81%和14.52%)，手術切口也髮生感染，主要受患者體重指數、Dukes分期、是否閤併糖尿病及手術類彆有關。結論肥胖、是否患有糖尿病及癌癥分期等影響結直腸癌患者化療後感染，以革蘭陰性桿菌為主。醫院有責任採取措施預防感染。
목적：관찰결직장암환자경과화료후감염병원균적분포병분석기영향인소。방법선취아원우2013년3월~2015년2월수치적260례결직장암환자，채집환자상구분비물작위표본병행세균배양，대병원균진행감정，병대기타가능영향병원균분포적인소진행분석。결과입선적260례환자중유62례출현화료후감염(23.85%)，제1차화료후감염적환자수위28례，제2차화료후감염적환자수위34례。주요발생감염부위위호흡도감염33례，소화도감염10례，피부급부건감염5례，비뇨도감염9례，기여부위감염5례。진행세균학분석검출결과견혁란음성균점69.35%(43/62)，혁란양성균점22.58%(14/62)，소점비례최대적시대장애희균여동록가단포균(분별위25.81%화14.52%)，수술절구야발생감염，주요수환자체중지수、Dukes분기、시부합병당뇨병급수술유별유관。결론비반、시부환유당뇨병급암증분기등영향결직장암환자화료후감염，이혁란음성간균위주。의원유책임채취조시예방감염。
Objective To study the distribution of pathogens from infected surgical incision in colorectal cancer and its influence factor associated with incisional surgical site infection. Methods 260 patients after chemotherapy were involved in this study .The incision of secretion were col ected for bacterial culture to separate and identify pathogens. The suspicious factors such as age, gender, body mass index, diabetes and other complications and tumor stage were used to analysis the relationship between infection and these factors after chemotherapy. Results 62 cases of 260 patients were infected (23.85%). 28 patients were infected after the first dose of chemotherapy, and the remaining 34 cases occur ed within the first two times after chemotherapy. The infection mainly occur ed in respiratory tract (33 cases),gastrointestinal (10 cases),urinary tract (9 cases), skin and accessories (5 cases),and other parts of body (5 cases).Most of the infection pathogens were Gram-negative bacil i (69.35%), Gram-positive bacil i (22.58%).The distribution of Escherichia coli with obesity and diabetes mel itus increased significantly ( <0.05).The incidences of SSI in patients was related to DUKES stage, BMI, diabetes, and operation type ( <0.05),and there was lit le cor ected with the age, gender and tumor type ( ﹥0.05).Conclusion Obesity, diabetes mel itus and tumor staging are the most important factors associated with SSI in colorectal cancer patients. Preventive measures for infections should be taken.
