CAJ | 학술논문

目的：观察非小细胞肺癌合并阻塞性肺炎患者单纯性125 I 粒子治疗的临床疗效。方法28例非小细胞肺癌合并阻塞性肺炎患者，术前应用治疗计划系统计算出目的病灶的剂量和布源方案，术中 CT 引导进行粒子组织间插植近距离放射性治疗，术后1~2月随访，观察疗效。结果疗效评价总有效率分别为89.3%，临床症状以胸闷、气短和发热改善明显，生活质量以食欲及精神改善明显，血常规示白细胞降低明显。结论单纯性125 I 粒子治疗非小细胞肺癌合并阻塞性肺炎患者疗效确切。
목적：관찰비소세포폐암합병조새성폐염환자단순성125 I 입자치료적림상료효。방법28례비소세포폐암합병조새성폐염환자，술전응용치료계화계통계산출목적병조적제량화포원방안，술중 CT 인도진행입자조직간삽식근거리방사성치료，술후1~2월수방，관찰료효。결과료효평개총유효솔분별위89.3%，림상증상이흉민、기단화발열개선명현，생활질량이식욕급정신개선명현，혈상규시백세포강저명현。결론단순성125 I 입자치료비소세포폐암합병조새성폐염환자료효학절。
Objective To observe the curative effect of pure 1 25 I treatment to non-small cell lung cancer combined obstructive pneumonia.Methods 28 cases with non-small cell lung cancer combined obstructive pneumonia were enrolled.Treatment planning system was used to calculate the dosage of tumor and make up the therapeutic plan.CT-guided radiation treatment of particle im-plantation was then conducted.Follow-up was done to evaluate the curative effect one to two months after treatment.Results The total effective rate of therapeutic evaluation was 89.3%.Clinical symptoms including chest distress,hard breathing and fever were ameliorated remarkedly.Life quality score of appetite and fatigue was also improved.White blood cell reduced significantly in blood routine examination.Conclusion There is a definite curative effect of pure 1 25 I treatment to non-small cell lung cancer combined ob-structive pneumonia.