药学实践杂志
藥學實踐雜誌
약학실천잡지
Journal of Pharmaceutical Practice
2015年
5期
401-405
,共5页
网络药理学%生物网络%网络构建%网络分析
網絡藥理學%生物網絡%網絡構建%網絡分析
망락약이학%생물망락%망락구건%망락분석
network pharmacology%biological network%network construction%network analysis
网络药理学是近年来研究较热的一门新兴的药理学分支学科。以其“多基因,多靶点”的特点与复杂疾病的治疗理念相吻合。区别于传统繁复的药理学实验方法,网络药理学以其独特的研究方法获取药物与靶点相关的信息,既节省时间又节省费用。该文通过检索中国知网和PubM ed数据库,从网络构建、网络分析、实验验证3个方面介绍了网络药理学的研究方法,并阐述其应用进展,为深入研究药理学领域拓展新的思路。
網絡藥理學是近年來研究較熱的一門新興的藥理學分支學科。以其“多基因,多靶點”的特點與複雜疾病的治療理唸相吻閤。區彆于傳統繁複的藥理學實驗方法,網絡藥理學以其獨特的研究方法穫取藥物與靶點相關的信息,既節省時間又節省費用。該文通過檢索中國知網和PubM ed數據庫,從網絡構建、網絡分析、實驗驗證3箇方麵介紹瞭網絡藥理學的研究方法,併闡述其應用進展,為深入研究藥理學領域拓展新的思路。
망락약이학시근년래연구교열적일문신흥적약이학분지학과。이기“다기인,다파점”적특점여복잡질병적치료이념상문합。구별우전통번복적약이학실험방법,망락약이학이기독특적연구방법획취약물여파점상관적신식,기절성시간우절성비용。해문통과검색중국지망화PubM ed수거고,종망락구건、망락분석、실험험증3개방면개소료망락약이학적연구방법,병천술기응용진전,위심입연구약이학영역탁전신적사로。
Recently ,network pharmacology was a pop emerging pharmacology branch .The theory of "multi-gene , multi-target"about network pharmacology was consistent with treatment of complex disease .Different from the traditional ex-perimental methods about pharmacology ,the research methods of network pharmacology uniquely obtain the information of drugs and relative targets with less time and less money .In this paper ,according to the searching of China Knowledge Re-source Integrated Database and PubMed ,three aspects about research methods of network pharmacology together with its ap-plications were introduced :network construction ,network analysis and experimental validation .The introductions of the meth-ods gave us a new vision in researching the field of pharmacology deeply .