CAJ | 학술논문

目的：探讨注射用头孢西丁钠的安全性和不良反应。方法病例60张，处方60张，分析注射头孢西丁钠后发生的不良反应比率。结果本组研究中，用药不良反应包括呕吐1例，腹痛腹泻1例，过敏8例，发热1例，头痛1例，血管痛3例。其中包括合并热毒宁注射液发生不良反应发生呕吐1例，过敏7例，发热1例，头痛1例，血管痛2例，总发生率为30.00%（12/40）；合并氨溴索针发生不良反应情况为，腹痛腹泻1例，过敏1例，血管痛1例，总比例为21.43（3/14）。合并其他药物无不良反应发生。结论注射用头孢西丁钠可发生过敏、发热、胃肠道不适等的不良反应，用药前应严格按照要求，并进行过敏性试验和联合用药实验，用药过程中密切关注患者反应，不良反应剧烈时立即停止用药。
목적：탐토주사용두포서정납적안전성화불량반응。방법병례60장，처방60장，분석주사두포서정납후발생적불량반응비솔。결과본조연구중，용약불량반응포괄구토1례，복통복사1례，과민8례，발열1례，두통1례，혈관통3례。기중포괄합병열독저주사액발생불량반응발생구토1례，과민7례，발열1례，두통1례，혈관통2례，총발생솔위30.00%（12/40）；합병안추색침발생불량반응정황위，복통복사1례，과민1례，혈관통1례，총비례위21.43（3/14）。합병기타약물무불량반응발생。결론주사용두포서정납가발생과민、발열、위장도불괄등적불량반응，용약전응엄격안조요구，병진행과민성시험화연합용약실험，용약과정중밀절관주환자반응，불량반응극렬시립즉정지용약。
Objective To discuss the safety and adverse reactions of cefoxitin sodium injection. Methods 60 cases and 60 prescriptions were selected and the incidence of adverse reactions after injecting cefoxitin sodium were analyzed. Results Adverse reactions included 1 case of vomiting, 1 case of abdominal pain and diarrhea, 8 cases of allergy, 1 case of fever, 1 case of headache, 3 cases of vascular pain, and among which 12 cases were combined with Reduning injection and its total incidence was 30.00%(12/40), 3 cases were combined with Ambroxo injection and its total incidence was 21.43% (3/14). Conclusion Cefoxitin sodium injection can cause allergies, fever, gastrointestinal discomfort and other adverse reactions, so before the medication and allergy tests and experimental combination therapy should be run strictly. In the medication process we should pay close attention to the patient's response, when severe adverse reactions occur we must immediately stop the medication.