CAJ | 학술논문

目的：分析比较阿司匹林与氯吡格雷治疗老年冠心病的临床疗效。方法选择老年冠心病患者96例作为研究对象，按治疗方法的不同，分为对照组（n=48例）和观察组（n=48例），对照组给予单纯阿司匹林治疗，观察组给予氯吡格雷治疗，对两组患者的临床效果进行分析比较。结果两组患者治疗前的 PAG、PT、APTT 指标比较差异不显著（P＞0.05）；观察组治疗后的 PAG、PT、APTT 指标分别为（31.26±5.23）%、（14.38±2.67）s、（40.23±2.34）s，优于对照组与的（43.78±8.43）%、（12.87±1.89）s、（48.51±1.67）s，差异有统计学意义（P ＜0.05）；观察组胃黏膜出血率为4.17%，对照组胃黏膜出血率为12.50%，差异有统计学意义（P ＜0.05）。结论老年冠心病采取氯吡格雷治疗的临床效果显著，且安全性好。
목적：분석비교아사필림여록필격뢰치료노년관심병적림상료효。방법선택노년관심병환자96례작위연구대상，안치료방법적불동，분위대조조（n=48례）화관찰조（n=48례），대조조급여단순아사필림치료，관찰조급여록필격뢰치료，대량조환자적림상효과진행분석비교。결과량조환자치료전적 PAG、PT、APTT 지표비교차이불현저（P＞0.05）；관찰조치료후적 PAG、PT、APTT 지표분별위（31.26±5.23）%、（14.38±2.67）s、（40.23±2.34）s，우우대조조여적（43.78±8.43）%、（12.87±1.89）s、（48.51±1.67）s，차이유통계학의의（P ＜0.05）；관찰조위점막출혈솔위4.17%，대조조위점막출혈솔위12.50%，차이유통계학의의（P ＜0.05）。결론노년관심병채취록필격뢰치료적림상효과현저，차안전성호。
Objective To analyze the clinical effect of aspirin and clopidogrel in the treatment of coronary heart disease. Methods 96 elderly patients with coronary heart disease (CHD) were divided into control group (n=48) and observation group (n=48 cases). The control group was treated with aspirin, and the clinical effect of the two groups was analyzed and compared. Results Two groups of patients before treatment, PT, APTT, PAG index were not significantly different (P>0.05), PAG, APTT, PT index were (31.26±5.23) %, (14.38±2.67) s, (40.23±2.34) s, better than the control group (43.78±8.43)%, (8.43±12.87) s, (1.89±1.67) s, the difference was statistically significant (P<0.05), the control group was 12.50%, the difference was statistically significant (P<0.05). Conclusion Elderly patients with coronary heart disease treated with clopidogrel, the clinical effect is significant, and the safety is good.