中国继续医学教育
中國繼續醫學教育
중국계속의학교육
China Continuing Medical Education
2015年
25期
175-176
,共2页
妊娠高血压%短效%长效%硝苯地平%临床效果
妊娠高血壓%短效%長效%硝苯地平%臨床效果
임신고혈압%단효%장효%초분지평%림상효과
Pregnancy with hypertension%Short-acting%Long-acting%Nifedipine%Clinical effect
目的：分析短效与长效硝苯地平治疗妊娠高血压的疗效差异性。方法连续选取我院2012年2月～2014年2月收治的89例妊娠高血压患者作为研究对象，该研究取得我院伦理委员会通过及患者、家属的知情同意权后，采用随机数字法将患者分为短效硝苯地平组（n=42）及长效硝苯地平组（n=47）。对两组患者治疗后的血压变化情况进行分析，同时观察产妇分娩方式及围生儿结局等情况。结果治疗前两组患者的平均收缩压、平均舒张压和平均动脉压的比较，差异均无统计学意义（P ＞0.05）；治疗后两组患者的平均收缩压、平均舒张压和平均动脉压均下降，且长效组比短效组降低更明显，差异均有统计学意义（P ＜0.05）。结论长效硝苯地平治疗妊娠期高血压具有重要的临床价值，降压效果显著，减少了母婴不良结局的发生。
目的：分析短效與長效硝苯地平治療妊娠高血壓的療效差異性。方法連續選取我院2012年2月～2014年2月收治的89例妊娠高血壓患者作為研究對象，該研究取得我院倫理委員會通過及患者、傢屬的知情同意權後，採用隨機數字法將患者分為短效硝苯地平組（n=42）及長效硝苯地平組（n=47）。對兩組患者治療後的血壓變化情況進行分析，同時觀察產婦分娩方式及圍生兒結跼等情況。結果治療前兩組患者的平均收縮壓、平均舒張壓和平均動脈壓的比較，差異均無統計學意義（P ＞0.05）；治療後兩組患者的平均收縮壓、平均舒張壓和平均動脈壓均下降，且長效組比短效組降低更明顯，差異均有統計學意義（P ＜0.05）。結論長效硝苯地平治療妊娠期高血壓具有重要的臨床價值，降壓效果顯著，減少瞭母嬰不良結跼的髮生。
목적：분석단효여장효초분지평치료임신고혈압적료효차이성。방법련속선취아원2012년2월～2014년2월수치적89례임신고혈압환자작위연구대상，해연구취득아원윤리위원회통과급환자、가속적지정동의권후，채용수궤수자법장환자분위단효초분지평조（n=42）급장효초분지평조（n=47）。대량조환자치료후적혈압변화정황진행분석，동시관찰산부분면방식급위생인결국등정황。결과치료전량조환자적평균수축압、평균서장압화평균동맥압적비교，차이균무통계학의의（P ＞0.05）；치료후량조환자적평균수축압、평균서장압화평균동맥압균하강，차장효조비단효조강저경명현，차이균유통계학의의（P ＜0.05）。결론장효초분지평치료임신기고혈압구유중요적림상개치，강압효과현저，감소료모영불량결국적발생。
Objective To study the clinical effect of short and long-acting nifedipine for pregnancy patients with hypertension. Methods A total of 89 consecutives diagnosed as pregnancy with hypertension from February 2012 to February 2014 were divided into short-acting nifedipine group (n=42) and long-acting nifedipine group (n=47) by the random number method after getting approval of our hospital' ethics committee and the informed consent right of patients and family members. then to compare differences of the mean systolic pressure, diastolic pressure and mean arterial pressure, the clinical effect and complications rate. Results The mean systolic pressure, diastolic pressure and mean arterial pressure before treatment in the two groups were no statistical difference (P>0.05). the mean systolic pressure, diastolic pressure and mean arterial pressure after treatment were all lower than before in the two groups and they in long-acting nifedipine group were significantly lower than short-acting nifedipine group (P<0.05). the vaginal delivery rate in the long-acting nifedipine group were significantly higher, the maternal preeclampsia, intrauterine asphyxia, perinatal mortality and fetal adverse outcomes in total incidence rate were in significantly lower than short-acting nifedipine group (P<0.05). Conclusion The long-acting nifedipine could greatly improve clinical effect and decrease complications than short-acting nifedipine.
