中国医药指南
中國醫藥指南
중국의약지남
Guide of China Medicine
2015年
25期
9-9,11
,共2页
胃肠炎%惊厥%儿童%轮状病毒%苯巴比妥
胃腸炎%驚厥%兒童%輪狀病毒%苯巴比妥
위장염%량궐%인동%륜상병독%분파비타
Gastroenteritis%Convulsion%Children%Rotavirus%Phenobarbital
目的：研究良性惊厥并轻度胃肠炎（BICE）婴幼儿的临床特征、病因及治疗措施。方法对42例BICE的患儿详细观察记录其住院期间的胃肠炎及惊厥的表现特点。先后用金标法对患儿粪便行轮状病毒抗原，检测血生化（Na+，K+，Ca2+，Cl-，HCO-），跟踪随访半年以上。结果本病患儿胃肠症状多较轻微，无脱水或仅有轻度脱水；惊厥多为成簇发作；血生化（Na+，K+，Ca2+，Cl-，HCO-）正常或基本正常；脑脊液及头颅影像学检查正常；发作间期脑电图9例（21.4%）于中央中线或中央区或额区见少量痫样放电，1例中央中线及顶区见痫样波发放，其他32例正常或睡眠时背景活动稍差。轮状病毒抗原：粪便阳性23例。苯巴比妥预防性肌内注射1次后惊厥再发率为79.2%。结论婴幼儿BICE消化系统表现轻，惊厥往往成簇发作。巴比妥肌内注射对惊厥镇痉作用不明显，BICE后遗癫痫的概率很小。
目的：研究良性驚厥併輕度胃腸炎（BICE）嬰幼兒的臨床特徵、病因及治療措施。方法對42例BICE的患兒詳細觀察記錄其住院期間的胃腸炎及驚厥的錶現特點。先後用金標法對患兒糞便行輪狀病毒抗原，檢測血生化（Na+，K+，Ca2+，Cl-，HCO-），跟蹤隨訪半年以上。結果本病患兒胃腸癥狀多較輕微，無脫水或僅有輕度脫水；驚厥多為成簇髮作；血生化（Na+，K+，Ca2+，Cl-，HCO-）正常或基本正常；腦脊液及頭顱影像學檢查正常；髮作間期腦電圖9例（21.4%）于中央中線或中央區或額區見少量癇樣放電，1例中央中線及頂區見癇樣波髮放，其他32例正常或睡眠時揹景活動稍差。輪狀病毒抗原：糞便暘性23例。苯巴比妥預防性肌內註射1次後驚厥再髮率為79.2%。結論嬰幼兒BICE消化繫統錶現輕，驚厥往往成簇髮作。巴比妥肌內註射對驚厥鎮痙作用不明顯，BICE後遺癲癇的概率很小。
목적：연구량성량궐병경도위장염（BICE）영유인적림상특정、병인급치료조시。방법대42례BICE적환인상세관찰기록기주원기간적위장염급량궐적표현특점。선후용금표법대환인분편행륜상병독항원，검측혈생화（Na+，K+，Ca2+，Cl-，HCO-），근종수방반년이상。결과본병환인위장증상다교경미，무탈수혹부유경도탈수；량궐다위성족발작；혈생화（Na+，K+，Ca2+，Cl-，HCO-）정상혹기본정상；뇌척액급두로영상학검사정상；발작간기뇌전도9례（21.4%）우중앙중선혹중앙구혹액구견소량간양방전，1례중앙중선급정구견간양파발방，기타32례정상혹수면시배경활동초차。륜상병독항원：분편양성23례。분파비타예방성기내주사1차후량궐재발솔위79.2%。결론영유인BICE소화계통표현경，량궐왕왕성족발작。파비타기내주사대량궐진경작용불명현，BICE후유전간적개솔흔소。
Objective To study the benign convulsions with mild gastroenteritis (BICE) clinical characteristics, etiology and treatment of infants and young children.Methods 42 cases of BICE patients with observed features recorded gastroenteritis and convulsions during their hospital stay. The blood biochemical(Na+, K+, Ca2+, Cl-, HCO-) of the stool rotavirus antigen of the children were detected by gold standard method, followed up for more than half year.Results The disease of children gastrointestinal symptoms more mild, no dehydration or only mild dehydration; convulsions clustered children;serum(Na+, K+, Ca2+, Cl-, HCO-) normal or nearly normal; of cerebrospinal lfuid and brain imaging examination was normal; seizure interictal EEG in 9 cases (21.4%) in the central line or central or frontal region to see a small amount of epileptiform discharge, 1 case medial and apical area see epileptiform wave distribution, the other 32 cases normal or sleep background activity slightly worse. Rotavirus antigen: stool positive in 23 cases. After the ifrst injection of phenobarbital to prevent sexual convulsion recurrence rate was 79.2%.Conclusion BICE infant digestive system manifestations, convulsion attack in clusters. The intramuscular injection of pentobarbital convulsion antispasmodic effect is not obvious, the probability is very small after epilepsy BICE.
