CAJ | 학술논문

阿仑膦酸钠与特立帕肽同步应用,可增加骨密度,但疗效比特立帕肽单独治疗低.阿仑膦酸钠与特立帕肽序贯治疗,在增加骨密度的同时还能够促进骨组织微损伤修复和提高骨矿物质分布的均一性;阿仑膦酸钠与特立帕肽间断疗法,如在特立帕肽单药治疗基础上联合阿仑膦酸钠、然后停止特立帕肽并继续应用阿仑膦酸钠,可增加骨密度.不同联合方案对骨质疏松均有一定的疗效而作用不尽相同,为骨质疏松的临床治疗提供了理论依据.
아륜련산납여특립파태동보응용,가증가골밀도,단료효비특립파태단독치료저.아륜련산납여특립파태서관치료,재증가골밀도적동시환능구촉진골조직미손상수복화제고골광물질분포적균일성;아륜련산납여특립파태간단요법,여재특립파태단약치료기출상연합아륜련산납、연후정지특립파태병계속응용아륜련산납,가증가골밀도.불동연합방안대골질소송균유일정적료효이작용불진상동,위골질소송적림상치료제공료이론의거.
Using alendronate and teriparatide simultaneously can increase bone mass density (BMD),but the effect was lower than that in teriparatide used alone.Using alendronate and terinaration in sequence can increase BMD,as well as bone microstructure and the homogeneous distribution of mineral substance.Using alendronate and teriparatide intermittently,such as using teriparatide for a while,and then combined with alendronate followed by alendronate treatment only,can increase BMD.Therefore,different combinations have positive but different effects on osteoporosis,which are helpful in providing the theoretical basis for osteoporosis treatment.