CAJ | 학술논문

目的：探讨轻度脑外伤后磁敏感加权成像(SWI)图像异常与轻度脑外伤后引起的抑郁症之间的相关性。方法收集脑外伤后常规 CT 及 MRI 检查显示正常的患者资料180例。所有患者均行常规 MRI 平扫序列和 SWI 扫描，根据 SWI 图像计算微出血灶的体积与数量。对脑外伤患者在1年内进行随访，并根据 SCID-IV 标准将患者分为抑郁症组和非抑郁症组，比较抑郁症组与非抑郁症组 SWI 图像上微出血灶的差异。结果抑郁症组 SWI 图像异常率明显高于非抑郁症组(P <0.001)。在所有具有微出血灶的患者中，抑郁症组的微出血灶体积及数量明显高于非抑郁症组(P <0.001)，并且这种差异主要集中在额叶、顶叶及颞叶(P <0.001)。抑郁症组与非抑郁症组微出血灶体积及数量在其他部位未见明显差异(P >0.05)。结论SWI 可以有效地显示脑外伤后的微出血灶，脑外伤后引起的轻度抑郁与颅内微出血灶的部位及分布范围具有一定相关性。
목적：탐토경도뇌외상후자민감가권성상(SWI)도상이상여경도뇌외상후인기적억욱증지간적상관성。방법수집뇌외상후상규 CT 급 MRI 검사현시정상적환자자료180례。소유환자균행상규 MRI 평소서렬화 SWI 소묘，근거 SWI 도상계산미출혈조적체적여수량。대뇌외상환자재1년내진행수방，병근거 SCID-IV 표준장환자분위억욱증조화비억욱증조，비교억욱증조여비억욱증조 SWI 도상상미출혈조적차이。결과억욱증조 SWI 도상이상솔명현고우비억욱증조(P <0.001)。재소유구유미출혈조적환자중，억욱증조적미출혈조체적급수량명현고우비억욱증조(P <0.001)，병차저충차이주요집중재액협、정협급섭협(P <0.001)。억욱증조여비억욱증조미출혈조체적급수량재기타부위미견명현차이(P >0.05)。결론SWI 가이유효지현시뇌외상후적미출혈조，뇌외상후인기적경도억욱여로내미출혈조적부위급분포범위구유일정상관성。
Objective To evaluate the relationship between newly developed depression after mild traumatic brain injury (mild-TBI)and abnormality on susceptibility-weighted imaging (SWI).Methods One hundred and eighty patients after mild-TBI,who had normal findings at conventional CT and MRI were enrolled in our study.All cases underwent conventional MRI and SWI.Ac-cording to SWI,the number and volume of microbleed lesions were calculated.All patients were followed up within 1 year after TBI,and divided into depressive group and non-depressive group based on SCID-IV.The difference in microbleed lesions on SWI was compared between the depressive group and non-depressive group.Results The incidence rate of microbleed on SWI in depres-sive group was higher than that in non-depressive group (P < 0.001 ).Among patients with microbleed lesions,the volume and number of lesions in depressive group were more than those in non-depressive group (P <0.001),and these differences were only found at the frontal,parietal and temporal lobes (P < 0.001 ).No significantly difference between depressive and non-depressive group was found in other areas (P >0.05).Conclusion SWI is useful to identify the microbleed lesions after mild TBI.The depres-sion after TBI is correlated with the location and distribution range of microbleed lesions.