CAJ | 학술논문

目的：探讨阿卡波糖联合社区干预对预混胰岛素血糖控制不佳的2型糖尿病（T2DM ）患者的影响。方法选取某社区采用预混胰岛素进行血糖控制且控制不佳的 T2DM 患者100例，随机分为观察组和对照组，每组各50例。对照组患者给予皮下注射胰岛素的常规治疗，观察组患者在常规治疗的基础上加用阿卡波糖联合社区干预进行治疗，疗程3个月，观察两组患者治疗前后的餐前、餐后血糖，糖化血红蛋白，C 肽，胰岛素抵抗指数的变化情况。比较两组患者对糖尿病相关知识的掌握情况，社区管理评分结果、患者社会支持情况。结果治疗后，观察组患者的餐前、餐后血糖，糖化血红蛋白，C 肽，胰岛素抵抗指数均低于对照组患者，差异有统计学意义（P＜0．01）。观察组患者对糖尿病相关知识的掌握，社区管理评分及患者的社会支持均显著优于对照组患者（ P ＜0．01）。结论阿卡波糖联合社区干预对预混胰岛素血糖控制不佳的 T2DM 患者疗效明显，有助于提高患者的生活质量。
목적：탐토아잡파당연합사구간예대예혼이도소혈당공제불가적2형당뇨병（T2DM ）환자적영향。방법선취모사구채용예혼이도소진행혈당공제차공제불가적 T2DM 환자100례，수궤분위관찰조화대조조，매조각50례。대조조환자급여피하주사이도소적상규치료，관찰조환자재상규치료적기출상가용아잡파당연합사구간예진행치료，료정3개월，관찰량조환자치료전후적찬전、찬후혈당，당화혈홍단백，C 태，이도소저항지수적변화정황。비교량조환자대당뇨병상관지식적장악정황，사구관리평분결과、환자사회지지정황。결과치료후，관찰조환자적찬전、찬후혈당，당화혈홍단백，C 태，이도소저항지수균저우대조조환자，차이유통계학의의（P＜0．01）。관찰조환자대당뇨병상관지식적장악，사구관리평분급환자적사회지지균현저우우대조조환자（ P ＜0．01）。결론아잡파당연합사구간예대예혼이도소혈당공제불가적 T2DM 환자료효명현，유조우제고환자적생활질량。
Objective To investigate the effect of acarbose combined with the community interventions on T2DM patients with poor glycemic control by premixed insulin .Methods 100 cases of T2DM with poor glycemic control by premixed insulin in a community were selected and randomly divided into the observation group and the control group ,50 cases in each group .The control group was treated with the conventional treatment of insulin by subcutaneous injection ,while on this basis the observation group was added with acarbose combined with the commu‐nity interventions treatment .The treatment lasted for 3 months .Fasting and postprandial blood glucose ,glycated he‐moglobin ,C peptide ,insulin resistance index before and after treatment were observed in the two groups .The grasp‐ing situation of diabetes‐related knowledge ,community management score result and social support situation of the patients were compared between the two groups .Results Fasting and postprandial blood glucose ,glycated hemoglo‐bin ,C peptide and insulin resistance index after treatment in the observation group were lower than those in the con‐trol group ,the differences were statistically significant(P< 0 .01) ;the grasp of diabetes‐related knowledge ,communi‐ty management score and social support of the patients in the observation group were better than those in the control group(P< 0 .01) .Conclusion Acarbose combined with the community interventions has obvious effect for the treat‐ment of T2DM patients with poor glycemic control by premixed insulin and conduces to improve the life quality of the patients .