CAJ | 학술논문

目的探讨阿尔茨海默病(AD)家庭生活负担及其影响因素.方法采用整群抽样方法,选择太原市2家三甲医院及3个社区168例已确诊AD患者的照料者为研究对象,通过照料者负担量表(CBI)和家庭负担量表(FBS)收集信息.路径分析探讨照料者负担影响因素,家庭负担总分单因素和多因素分析分别采用t检验、单因素方差分析和多重线性回归.结果照料者负担总分为52.41±17.07;患者的认知水平对照料者负担影响有直接效应(标准化β=-0.280,P＜0.001)和间接效应,患者的日常行为能力对照料者负担有间接效应.家庭负担总分为16.23±9.00.单因素分析显示,患者性别、年龄、文化程度、认知功能、日常行为能力、精神行为症状、抑郁和痴呆等级对FBS总分有影响(P＜0.05);多因素分析显示,影响FBS总分的因素包括患者性别(标准化β=0.280,P＜0.01)、认知功能(标准化β=-0.158,P=0.033)以及日常行为能力(标准化β=-0.155,P=0.039).结论 AD患者认知功能和日常行为能力对照料者及家庭负担影响较大,可据此制定措施以减轻AD患者家庭负担.
목적 탐토아이자해묵병(AD)가정생활부담급기영향인소.방법 채용정군추양방법,선택태원시2가삼갑의원급3개사구168례이학진AD환자적조료자위연구대상,통과조료자부담량표(CBI)화가정부담량표(FBS)수집신식.로경분석탐토조료자부담영향인소,가정부담총분단인소화다인소분석분별채용t검험、단인소방차분석화다중선성회귀.결과 조료자부담총분위52.41±17.07;환자적인지수평대조료자부담영향유직접효응(표준화β=-0.280,P＜0.001)화간접효응,환자적일상행위능력대조료자부담유간접효응.가정부담총분위16.23±9.00.단인소분석현시,환자성별、년령、문화정도、인지공능、일상행위능력、정신행위증상、억욱화치태등급대FBS총분유영향(P＜0.05);다인소분석현시,영향FBS총분적인소포괄환자성별(표준화β=0.280,P＜0.01)、인지공능(표준화β=-0.158,P=0.033)이급일상행위능력(표준화β=-0.155,P=0.039).결론 AD환자인지공능화일상행위능력대조료자급가정부담영향교대,가거차제정조시이감경AD환자가정부담.
Objective To understand the family burden of Alzheimer' s disease (AD) and associated factors.Methods The subjects were 168 caregivers of patients with AD selected from two class 3A hospitals and three communities in Taiyuan through cluster sampling.The data were collected by using the Caregiver Burden Inventory (CBI) and the Family Burden Scale (FBS) of diseases.Path analysis was applied to identify the factors associated with the total score of CBI.T-test and One-way analysis of variance were applied to identify the factors associated with the total score of FBS.Multiple linear regression analysis was applied to identify the factors associated with family burden of AD.Results The total score of the caregivers' burden was 52.41 ± 17.07.AD patients' cognitive function had direct (standardized β =-0.280,P＜0.001) and indirect effect on CBI;while daily performance of AD patients had indirect effect on CBI.The total score of family burden was 16.23 ± 9.00.Univariate analysis showed that the sex,age,education level,cognitive function,daily performance,mental status,depression and dementia rating of AD patients might affect the total score of FBS (P ＜ 0.05).Multivariate analysis showed that the factors which affected the total score of FBS included the sex (standardizedβ =0.280,P ＜ 0.01),cognitive function (standardizedβ =-0.158,P =0.033) and daily performance of AD patients (standardizedβ=-0.155,P=0.039).Conclusion The caregiver and family burden of AD was mainly associated with the cognitive function and daily performance of AD patients.It is necessary to take targeted measures to reduce the caregiver and family burden of AD.