CAJ | 학술논문

目的：探讨应用组织工程技术中的支架技术和生长因子技术，在上颌后牙区重建种植体周围骨组织与软组织的临床成效。方法：选择上颌后牙区牙缺失伴骨量不足患者20例，随机分实验组对照组；实验组非细胞型组织工程技术重建上颌种植体周围组织。对照组使用常规重建种植体周围组织。精度修复后3、6、12月后以种植体动度仪测定法、曲面断层扫描法、 CT多平面重建法、牙周指数测定法分别检测。结果：实验组种植体动度值、种植体周围边缘骨高度值、骨密度CT值、种植体生物学宽度值、种植体周围牙龈指数、种植体周围牙龈出血指数和种植体周围菌斑指数也明显优于对照组(P<0.01)。结论：非细胞型组织工程技术可有效重建上颌种植体周围组织，对提升种植修复的远期疗效具有重要的临床意义。
목적：탐토응용조직공정기술중적지가기술화생장인자기술，재상합후아구중건충식체주위골조직여연조직적림상성효。방법：선택상합후아구아결실반골량불족환자20례，수궤분실험조대조조；실험조비세포형조직공정기술중건상합충식체주위조직。대조조사용상규중건충식체주위조직。정도수복후3、6、12월후이충식체동도의측정법、곡면단층소묘법、 CT다평면중건법、아주지수측정법분별검측。결과：실험조충식체동도치、충식체주위변연골고도치、골밀도CT치、충식체생물학관도치、충식체주위아간지수、충식체주위아간출혈지수화충식체주위균반지수야명현우우대조조(P<0.01)。결론：비세포형조직공정기술가유효중건상합충식체주위조직，대제승충식수복적원기료효구유중요적림상의의。
Objective:To evaluate the clinic effects of cell free-tissue engineering technique in maxillary per-i-implant tissue reconstruction. Methods:A randomized controlled experiment was conducted. 20 adult patients with two or three teeth loss and bone defect in posterior maxilla were divided into two groups, experimented groups and controlled groups. Experimented groups were adopted cell free-tissue engi-neering technique to reconstruct maxillary peri-implant tissue, while controlled groups were adopted the regular one. Finally, implant-supported prosthetics were applied in both groups. Marginal bone levels and soft tissue alterations of peri-implants were measured through taking x-ray periapical films after 1,3 and 5 monthes of prosthetic loading. Results: Implant mobility index, height of peri-implant marginal bone, biological width of implants, peri-implant gingival index, peri-implant gingival bleeding index and peri-implant plaque index in experimented groups are much better than the controlled one (P<0.01). Conclusion: Cell free-tissue engineering technique could reconstruct maxillary peri-implant tissue effectively and would contribute a lot in improving the long-term success rate of dental implant prosthetics.