医药前沿
醫藥前沿
의약전연
Yiayao Qianyan
2015年
25期
29-31,32
,共4页
痔%病理生理%缺血缺氧
痔%病理生理%缺血缺氧
치%병리생리%결혈결양
Hemorrhoid%Pathological physiology%Ischemia hypoxia
目前针对痔病的发病机制,国内外学者提出了各种假说进行解释。然而,痔病的发病原因及发病机制至今尚不清楚,因此目前的治疗方法只是缓解或消除痔病的症状。在本综述中,笔者对与痔病密切相关的病理生理学的研究进展进行了分析和讨论,包括肛管静息压升高、肛管黏膜上皮损伤、肛垫支持组织的变化、血管及血流的变化、生化指标的变化等,并提出下消化道末端缺血缺氧可能是痔形成机制这一新的假说。
目前針對痔病的髮病機製,國內外學者提齣瞭各種假說進行解釋。然而,痔病的髮病原因及髮病機製至今尚不清楚,因此目前的治療方法隻是緩解或消除痔病的癥狀。在本綜述中,筆者對與痔病密切相關的病理生理學的研究進展進行瞭分析和討論,包括肛管靜息壓升高、肛管黏膜上皮損傷、肛墊支持組織的變化、血管及血流的變化、生化指標的變化等,併提齣下消化道末耑缺血缺氧可能是痔形成機製這一新的假說。
목전침대치병적발병궤제,국내외학자제출료각충가설진행해석。연이,치병적발병원인급발병궤제지금상불청초,인차목전적치료방법지시완해혹소제치병적증상。재본종술중,필자대여치병밀절상관적병리생이학적연구진전진행료분석화토론,포괄항관정식압승고、항관점막상피손상、항점지지조직적변화、혈관급혈류적변화、생화지표적변화등,병제출하소화도말단결혈결양가능시치형성궤제저일신적가설。
For the pathogenesis of hemorrhoids. At present, the domestic and foreign scholars have proposed all sorts of hypotheses to explain. Hemorrhoids sickness, however, the etiology and pathogenesis is still unclear, so the treatment is to alleviate or eliminate the symptoms of hemorrhoids sickness. In this review, the author and the pathophysiology of hemorrhoids disease is closely related to the progress of research on are analyzed and discussed, including anal resting pressure, anal canal mucosa epithelial damage, anal cushion support organizational change, the change of the blood vessels and blood flow, the change of biochemical index, etc., and puts forward the end of the digestive tract ischemia hypoxia may be hemorrhoid formation mechanism of this new hypothesis.