CAJ | 학술논문

目的：探讨1?5T MRI磁疗对小鼠烫伤创面修复的影响。方法取健康雄性和雌性小鼠各14只，将砝码于沸水中加热10 min后置于经脱毛处理的小鼠背部皮肤，建立深Ⅱ度烫伤模型（病理切片证实）。成模后雄性小鼠和雌性小鼠均随机分为2组，即实验组和对照组，每组7只：（1）实验组小鼠创面在涂抹凡士林的同时接受磁疗，磁场强度为1?5T，每天治疗1次，每次30 min，共治疗12 d；（2）对照组小鼠创面单纯外涂凡士林治疗。分别于磁疗前（第0天）及磁疗后第3、6、9、12天观察两组小鼠创面修复情况。结果实验组和对照组小鼠创面面积在各观察时间点均无明显统计学差异，病理结果亦无明显组织学差异；而磁疗第3、6、9天，雄性和雌性实验组小鼠创面恢复情况均存在统计学差异。结论1?5T MRI磁疗对小鼠烫伤创面的修复作用不显著。
목적：탐토1?5T MRI자료대소서탕상창면수복적영향。방법취건강웅성화자성소서각14지，장겁마우비수중가열10 min후치우경탈모처리적소서배부피부，건립심Ⅱ도탕상모형（병리절편증실）。성모후웅성소서화자성소서균수궤분위2조，즉실험조화대조조，매조7지：（1）실험조소서창면재도말범사림적동시접수자료，자장강도위1?5T，매천치료1차，매차30 min，공치료12 d；（2）대조조소서창면단순외도범사림치료。분별우자료전（제0천）급자료후제3、6、9、12천관찰량조소서창면수복정황。결과실험조화대조조소서창면면적재각관찰시간점균무명현통계학차이，병리결과역무명현조직학차이；이자료제3、6、9천，웅성화자성실험조소서창면회복정황균존재통계학차이。결론1?5T MRI자료대소서탕상창면적수복작용불현저。
Objective To investigate the effect of magnetotherapy on rat scalding wound repair. Methods Healthy adult male and female rats, 14 for each sex, were used. Weights heated in boiling water for 10 minutes were put on the denuded back skin of rats to establish the model of deepⅡdegree scald burn wounds ( confirmed by pathological slice ex?amination) . After the model was established, male and female rats were randomly divided into the experimental group and the control group respectively, 7 for each group:(1) At the same time of smearing vaseline on the wounds, the experimen?tal group also received magnetotherapy once a day for 12 days, 30 minutes each time. The intensity of magnetic field was 1?5 T. ( 2 ) The control group was treated with only external use of vaseline and no magnetotherapy. Observe the skin wound healing state on the day before magnetotherapy (day 0), 3rd day, 6th day, 9th day and 12th day of magnetotherapy, respectively. Results There was no statistical difference or histological difference when compared the experimental group with the control group at any observation time point;there was statistical difference between the male experimental group and female experimental group on the 3rd day, 6th day, 9th day. Conclusion Magnetotherapy has no obvious repairing effect on scalding wound in rats.