CAJ | 학술논문

目的：以“原位再生医疗技术治疗糖尿病足”（ MEBO?DFU）的规范化流程作为临床应用研究基础，对MEBO?DFU原位再生终止截肢关键节点（ Key Nodes， KN）的机制进行辨析，为临床应用理清思路。方法临床总结发现，每个MEBO?DFU规范应用原位再生医疗技术治疗的关键节点都是在对应关键控制点（ Criti?cal Control Point， CCP）的掌控下实施的，关键节点的相互连接保障了原位再生医疗技术的临床效果，终止了DFU的截肢手术，实现了创面的原位再生愈合。结果 MEBO?DFU为创面的原位再生创造了生理生态条件，通过溃疡创面的原位再生保留了已坏死的肢、趾，且复发率低，这些效果决定于各个关键节点的正确掌控与实施。结论把握好MEBO?DFU终止截肢的关键节点和与之对应的关键控制点，既是严格规范的原位再生医疗技术实现MEBO?DFU终止截肢与创面原位再生的基础，也是MEBO?DFU规范应用、保障疗效、制定可行治疗规范程序的依据。
목적：이“원위재생의료기술치료당뇨병족”（ MEBO?DFU）적규범화류정작위림상응용연구기출，대MEBO?DFU원위재생종지절지관건절점（ Key Nodes， KN）적궤제진행변석，위림상응용리청사로。방법림상총결발현，매개MEBO?DFU규범응용원위재생의료기술치료적관건절점도시재대응관건공제점（ Criti?cal Control Point， CCP）적장공하실시적，관건절점적상호련접보장료원위재생의료기술적림상효과，종지료DFU적절지수술，실현료창면적원위재생유합。결과 MEBO?DFU위창면적원위재생창조료생리생태조건，통과궤양창면적원위재생보류료이배사적지、지，차복발솔저，저사효과결정우각개관건절점적정학장공여실시。결론파악호MEBO?DFU종지절지적관건절점화여지대응적관건공제점，기시엄격규범적원위재생의료기술실현MEBO?DFU종지절지여창면원위재생적기출，야시MEBO?DFU규범응용、보장료효、제정가행치료규범정서적의거。
Objective On the basis of the standard procedure of DFU treatment with in situ regeneration medical technology ( MEBO?DFU) , to differentiate and analyze the mechanism of MEBO?DFU Key Node ( KN) preventing the am?putation by in situ regeneration, and make a clear thinking for clinical application of MEBO?DFU. Methods According to the summaries of clinical application of MEBO?DFU, each Key Node of standard application of MEBO?DFU treatment is carried out conforming with the corresponding Critical Control Point ( CCP) , and the connection of Key Nodes ensures the clinical effect of in situ regeneration medical technology, avoids the amputation of diabetic foot ulcers and realizes the regen?erative healing of wounds in situ. Results MEBO?DFU treatment provides physiological and ecological conditions for wound in situ regeneration by which the necrotic limb or toe with ulcer is saved and hardly relapses. The effect of MEBO?DFU depends on the control and implementation of each Key Node. Conclusion The seize of the Key Nodes and corre?sponding Critical Control Points of MEBO?DFU treatment avoiding the amputation of diabetic foot ulcers, is the basis of not only in situ regeneration of wounds to avoid amputation by strictly standard application of MEBO?DFU treatment, but also the standardized application of MEBO?DFU, guarantee of the efficacy and set up of the practicable standard treatment procedures.