CAJ | 학술논문

目的：对湖南地区2006~2013年早产儿视网膜病变(ROP)筛查随访和治疗情况进行总结。方法回顾性分析ROP筛查诊治小组8年间对我院新生儿科就诊和我省ROP转诊网络医院转送的早产儿进行眼底筛查、手术和随访情况；对ROP、严重ROP及特殊ROP的发病情况，冷冻和激光手术成功率和并发症发生率进行分析。结果共有ROP 2512例，其中行视网膜手术536例。ROP发病性别无明显差异，>0.05；BA<32w早产儿发病率明显高于BA≥32w，<0.05；BW<1500g早产儿发病率明显高于BW≥1500g ，<0.01；双胎多胎早产儿发病率明显高于单胎，<0.05。ROP、严重ROP的发生率和致盲率随着规范的筛查治疗而逐年下降。激光手术并发症较冷冻手术少，但需要多次手术者较冷冻为多，<0.05。结论 BW<1500g，BA<32w及多胎妊娠是ROP发生的高风险因素。及时筛查和合理手术大大降低了ROP发生率和致盲率。激光手术较冷冻手术风险小，预后好。
목적：대호남지구2006~2013년조산인시망막병변(ROP)사사수방화치료정황진행총결。방법회고성분석ROP사사진치소조8년간대아원신생인과취진화아성ROP전진망락의원전송적조산인진행안저사사、수술화수방정황；대ROP、엄중ROP급특수ROP적발병정황，냉동화격광수술성공솔화병발증발생솔진행분석。결과공유ROP 2512례，기중행시망막수술536례。ROP발병성별무명현차이，>0.05；BA<32w조산인발병솔명현고우BA≥32w，<0.05；BW<1500g조산인발병솔명현고우BW≥1500g ，<0.01；쌍태다태조산인발병솔명현고우단태，<0.05。ROP、엄중ROP적발생솔화치맹솔수착규범적사사치료이축년하강。격광수술병발증교냉동수술소，단수요다차수술자교냉동위다，<0.05。결론 BW<1500g，BA<32w급다태임신시ROP발생적고풍험인소。급시사사화합리수술대대강저료ROP발생솔화치맹솔。격광수술교냉동수술풍험소，예후호。
Objective To report our experience of retinopathy of prematurity (ROP) in Hunan Children’s Hospital (HNCH), central south of China over a 8-year period. Methods A retrospective review was made for all premature infants with a diagnosis of ROP at HNCH between 2006 and 2013. The annually ROP and severe ROP incidence, blindness rate, complications of cryotherapy and laser surgery were collected and risk factors of ROP were analyzed. Results 2512 infants were diagnosed ROP. Surgery was done in 536 infants. There was no difference of the incidence of ROP between male and female, >0.05. The incidence of ROP in BA<32w infants higher than BA≥32w, <0.05,BW<1500g infants higher than BW≥1500g, <0.01,multiple birth infants high-er than single birth infants, <0.05. ROP incidence and blindness ROP rate decreasing annually. Laser with low risk and better than cryotherapy but need more repeated surgery. Conclusions Low BW, low BA and multiple births are high risk factors for ROP. Timely screening and surgery intervention decrease the blindness rate of ROP. Laser surgery with good outcome and lower risk than cryotherapy.