CAJ | 학술논문

目的：研究图形视觉诱发电位（PVEP）在单眼先天性上睑下垂患者视力发育评估中的应用。方法2010年1月至2012年12月在我院门诊就诊的108例单眼先天性上睑下垂患儿行PVEP检查，分析比较患眼P100潜伏期及振幅较健眼的变化。结果所有患眼PVEP潜伏期较健眼均明显延长，振幅降低；中度先天性上睑下垂眼，在中、高空间频率刺激下，双眼潜伏期与振幅有显著差异（<0.05）；重度先天性上睑下垂眼，在各空间频率刺激下，双眼潜伏期与振幅有显著差异（<0.05）；在中、高空间频率刺激下，患眼与健眼的P100潜伏期平均差值15.3±5.7ms，振幅差值13.2±4.9μv。结论对于低龄不合作单眼先天性上睑下垂患儿，PVEP可以做为一种客观的、有效的视力检查手段，从而为先天性上睑下垂手术时机提供了客观依据。
목적：연구도형시각유발전위（PVEP）재단안선천성상검하수환자시력발육평고중적응용。방법2010년1월지2012년12월재아원문진취진적108례단안선천성상검하수환인행PVEP검사，분석비교환안P100잠복기급진폭교건안적변화。결과소유환안PVEP잠복기교건안균명현연장，진폭강저；중도선천성상검하수안，재중、고공간빈솔자격하，쌍안잠복기여진폭유현저차이（<0.05）；중도선천성상검하수안，재각공간빈솔자격하，쌍안잠복기여진폭유현저차이（<0.05）；재중、고공간빈솔자격하，환안여건안적P100잠복기평균차치15.3±5.7ms，진폭차치13.2±4.9μv。결론대우저령불합작단안선천성상검하수환인，PVEP가이주위일충객관적、유효적시력검사수단，종이위선천성상검하수수술시궤제공료객관의거。
Objective To explore the clinical application of pattern visual evoked potential (P-VEP) in u-nilateral ptosis. Methods 108 patients with unilateral ptosis underwent P-VEP examination under natural pupil. Change of P100 latency and amplitude was recorded and analysed. Results Compared with the normal, latency pro-longed and amplitude decreased in affected eyes. Under middle and high spatial frequency, binocular latency and amplitude had significant difference in medium ptosis. Binocular mean difference of P100 latency was 15.3±5.7ms and binocular mean difference of amplitude was 13.2±4.9μv. Under different spatial frequency, binocular latency and amplitude had significant difference in severe ptosis. Conclusions As to uncooperative children, P-VEP is a objective and effective examination of visual acuity. It can present objective evidence for operation timing of con-genital ptosis.