CAJ | 학술논문

儿童血液病患者自身免疫功能低下,同时治疗过程中反复化疗对患儿免疫系统和造血功能的进一步损害,导致血液病患者医院感染高发,其中尤其以耐药菌及真菌感染较常见;血液病患儿常见的耐药菌感染有以下几种:多重耐药的大肠埃希菌、肺炎克雷伯杆菌等肠杆菌科细菌;多重耐药的铜绿假单胞菌、鲍曼不动杆菌等非发酵菌;甲氧西林耐药的凝固酶阴性葡萄球菌、金黄色葡萄球菌及多重耐药的粪肠球菌和屎肠球菌等阳性耐药菌;现就上述耐药菌目前的治疗进展进行讨论.
인동혈액병환자자신면역공능저하,동시치료과정중반복화료대환인면역계통화조혈공능적진일보손해,도치혈액병환자의원감염고발,기중우기이내약균급진균감염교상견;혈액병환인상견적내약균감염유이하궤충:다중내약적대장애희균、폐염극뢰백간균등장간균과세균;다중내약적동록가단포균、포만불동간균등비발효균;갑양서림내약적응고매음성포도구균、금황색포도구균급다중내약적분장구균화시장구균등양성내약균;현취상술내약균목전적치료진전진행토론.
Children with hematological diseases usually accompanied by low autoimmune function,and repeated chemotherapy exacerbated the damage to their immune system and hematopoietic function.Those lead to high incidence of nosocomial infection,most of infection were caused by multi-drug resistant bacteria and fungi.The major infections in hematological children are the following:multi-drug resistant Escherichia coli/Klebsiella pneumonia bacteria;multi-drug resistance Pseudomonas and Acinetobacte;Methicillin-resistant coagulase negative Staphylococcus and aureus;multi-drug resistance Enterococcus faecium.This review presents updated treatment strategies from the published clinical literature and provides recommendations for clinical treatment of multi-drug resistant bacteria in children with hematonosis.