临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
Chinese Journal of Clinical Rational Drug Use
2015年
27期
1-2
,共2页
脑出血%昏迷%醒脑静注射液%盐酸纳洛酮注射液%治疗结果
腦齣血%昏迷%醒腦靜註射液%鹽痠納洛酮註射液%治療結果
뇌출혈%혼미%성뇌정주사액%염산납락동주사액%치료결과
Cerebral hemorrhage%Coma%Xingnaojing injection%Naloxone hydrochloride injection%Treatment out-come
目的：探讨醒脑静注射液联合盐酸纳洛酮注射液治疗脑出血伴昏迷患者的临床疗效。方法选取2013年3月—2015年3月临汾市人民医院收治的脑出血伴昏迷患者78例，随机分为观察组与对照组，各39例。两组患者均予以基础治疗，对照组患者予以盐酸纳洛酮注射液治疗，观察组患者在对照组基础上加用醒脑静注射液治疗。观察两组患者临床疗效、治疗前后格拉斯哥昏迷评分和脑血肿量、昏迷时间。结果观察组患者总有效率高于对照组，差异有统计学意义（P ﹤0.05）；治疗前两组患者格拉斯哥昏迷评分、脑血肿量比较，差异无统计学意义（ P ﹥0.05）；治疗后观察组患者格拉斯哥昏迷评分高于对照组，脑血肿量少于对照组，差异有统计学意义（ P ﹤0.05）；观察组患者昏迷时间短于对照组，差异有统计学意义（ P ﹤0.05）。结论醒脑静注射液联合盐酸纳洛酮注射液治疗脑出血伴昏迷患者的临床疗效显著，可促进患者意识恢复，降低脑血肿量，缩短昏迷时间。
目的：探討醒腦靜註射液聯閤鹽痠納洛酮註射液治療腦齣血伴昏迷患者的臨床療效。方法選取2013年3月—2015年3月臨汾市人民醫院收治的腦齣血伴昏迷患者78例，隨機分為觀察組與對照組，各39例。兩組患者均予以基礎治療，對照組患者予以鹽痠納洛酮註射液治療，觀察組患者在對照組基礎上加用醒腦靜註射液治療。觀察兩組患者臨床療效、治療前後格拉斯哥昏迷評分和腦血腫量、昏迷時間。結果觀察組患者總有效率高于對照組，差異有統計學意義（P ﹤0.05）；治療前兩組患者格拉斯哥昏迷評分、腦血腫量比較，差異無統計學意義（ P ﹥0.05）；治療後觀察組患者格拉斯哥昏迷評分高于對照組，腦血腫量少于對照組，差異有統計學意義（ P ﹤0.05）；觀察組患者昏迷時間短于對照組，差異有統計學意義（ P ﹤0.05）。結論醒腦靜註射液聯閤鹽痠納洛酮註射液治療腦齣血伴昏迷患者的臨床療效顯著，可促進患者意識恢複，降低腦血腫量，縮短昏迷時間。
목적：탐토성뇌정주사액연합염산납락동주사액치료뇌출혈반혼미환자적림상료효。방법선취2013년3월—2015년3월림분시인민의원수치적뇌출혈반혼미환자78례，수궤분위관찰조여대조조，각39례。량조환자균여이기출치료，대조조환자여이염산납락동주사액치료，관찰조환자재대조조기출상가용성뇌정주사액치료。관찰량조환자림상료효、치료전후격랍사가혼미평분화뇌혈종량、혼미시간。결과관찰조환자총유효솔고우대조조，차이유통계학의의（P ﹤0.05）；치료전량조환자격랍사가혼미평분、뇌혈종량비교，차이무통계학의의（ P ﹥0.05）；치료후관찰조환자격랍사가혼미평분고우대조조，뇌혈종량소우대조조，차이유통계학의의（ P ﹤0.05）；관찰조환자혼미시간단우대조조，차이유통계학의의（ P ﹤0.05）。결론성뇌정주사액연합염산납락동주사액치료뇌출혈반혼미환자적림상료효현저，가촉진환자의식회복，강저뇌혈종량，축단혼미시간。
Objective To explore the effect of Xingnaojing injection combined with naloxone hydrochloride injection in treating cerebral hemorrhage with coma. Methods A total of 78 patients with cerebral hemorrhage with coma were selected in the People's Hospital of Linfen from March 2013 to March 2015,they were randomly divided into observation group and control group,39 cases in each group. Two groups were given basic treatment,control group were given naloxone hydrochloride injec-tion treatment,observation group were given Xingnaojing injection treatment on the basis of control group. Clinical effect,be-fore and after treatment GCS and cerebral hematoma amount,coma time between the two groups were compared. Results The total effective rate of observation group was higher than that of control group(P ﹤ 0. 05);before treatment,GCS and cerebral hematoma amount showed no significant differences between the two groups(P ﹥ 0. 05);after treatment,GCS of observation group was higher than that of control group,cerebral hematoma amount of observation group was less than that of control group (P ﹤ 0. 05);coma time of observation group was shorter than that of control group(P ﹤ 0. 05). Conclusion Xingnaojing in-jection combined with naloxone hydrochloride injection have remarkable curative effect in the treatment of patients with cerebral hemorrhage with coma,can improve the patients' consciousness,reduce the amount of brain hematoma,shorten the coma time.
