CAJ | 학술논문

卡氏肺囊虫肺炎(PCP)是一种致命性机会性感染,多见于免疫缺陷患者.近年来,随着诊疗技术的进步,儿童血液病远期疗效显著提高,由于联合化疗、免疫抑制剂的应用及造血干细胞移植的开展,非人类免疫缺陷病毒(HIV)感染相关性PCP发生率明显升高.现对儿童血液病PCP的临床表现、辅助检查、诊断、治疗和预防进行综述.强调对高风险患者,应采用复方磺胺甲基异(噁)唑进行预防,从而有效降低PCP的发病率.
잡씨폐낭충폐염(PCP)시일충치명성궤회성감염,다견우면역결함환자.근년래,수착진료기술적진보,인동혈액병원기료효현저제고,유우연합화료、면역억제제적응용급조혈간세포이식적개전,비인류면역결함병독(HIV)감염상관성PCP발생솔명현승고.현대인동혈액병PCP적림상표현、보조검사、진단、치료화예방진행종술.강조대고풍험환자,응채용복방광알갑기이(오)서진행예방,종이유효강저PCP적발병솔.
Pneumocystis carinii pneumonia (PCP) is a life-threatening opportunistic infection in immunocompromised patients.In recent years,the incidence of PCP has increased significantly since the application of combined chemotherapy,immunosuppressant and hematopoietic stem cell transplantation,with improved long-term efficacy in pediatric blood disease.This review summarizes the clinical manifestations,laboratory and radiological examination,diagnosis,treatment and prophylaxis.Compound Sulfamethoxazole is the most commonly used agent for prophylaxis.It is recommended for the high-risk patients to take PCP prophylaxis,which could decrease the incidence of PCP.