CAJ | 학술논문

目的：探讨完全性葡萄胎与胎儿共存（CMCF）的临床特征及妊娠结局。方法收集并分析6例 CMCF 的临床资料。结果6例中，体外受精-胚胎移植术后妊娠5例，促排卵治疗后妊娠1例；妊娠中期发现5例，妊娠早期发现1例；双胎之一完全性葡萄胎5例，三胎之一完全性葡萄胎1例；要求继续妊娠1例，要求终止妊娠4例，被迫终止妊娠1例。6例产妇均存活，胎儿存活1例。结论CMCF 的发生可能与应用辅助生殖技术相关，其结局取决于病情发展、胎儿染色体及患者意愿。若胎儿染色体正常，且妊娠期间未出现严重母体并发症，有分娩活胎可能，但其继续妊娠的风险评估仍需进一步的研究。
목적：탐토완전성포도태여태인공존（CMCF）적림상특정급임신결국。방법수집병분석6례 CMCF 적림상자료。결과6례중，체외수정-배태이식술후임신5례，촉배란치료후임신1례；임신중기발현5례，임신조기발현1례；쌍태지일완전성포도태5례，삼태지일완전성포도태1례；요구계속임신1례，요구종지임신4례，피박종지임신1례。6례산부균존활，태인존활1례。결론CMCF 적발생가능여응용보조생식기술상관，기결국취결우병정발전、태인염색체급환자의원。약태인염색체정상，차임신기간미출현엄중모체병발증，유분면활태가능，단기계속임신적풍험평고잉수진일보적연구。
Objective To explore the clinical characteristics and pregnancy outcomes of complete hy-datidiform mole and co-existing fetus (CMCF).Methods The data of six CMCF women were analyzed retro-spectively.Results Among six CMCF women,five were pregnant after in vitro fertilization and embryo trans-plantation,and one after ovulation-stimulating treatment.Five patients were diagnosed with CMCF in middle pregnancy and one in early pregnancy.Five cases had twin pregnancy with complete hydatidiform mole and one was triplet pregnanct.One case insisted on continuous pregnancy,four accepted pregnancy termination and one was forced to terminate pregnancy.All six women and one fetus survived.Conclusions The incidence of CM-CF is probably correlated with the application of assisted reproductive technology.Clinical outcomes depend on disease progression,fetal chromosome and patients’willingness.If the fetal chromosome is normal and no seri-ous maternal complications occur during pregnancy,the fetus may survive.However,the risk of continuous pregnancy remains to be evaluated.