中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
Chinese Journal of the Frontiers of Medical Science (Electronic Version)
2015年
8期
120-122
,共3页
白癜风%自身免疫性疾病%横断面调查
白癜風%自身免疫性疾病%橫斷麵調查
백전풍%자신면역성질병%횡단면조사
Vitiligo%Autoimmune disease%Cross-sectional study
目的：调查分析白癜风患病人群常见相关自身免疫性疾病的患病情况，为白癜风患病人群自身免疫性疾病的防治提供参考。方法选取2007年1月至2014年5月于本院皮肤科就诊的978例白癜风患者为研究对象。经患者知情同意后，采用自行设计的调查问卷对入选患者进行流行病学调查，调查主要内容包括：患者基本情况、发病年龄、发病部位、自身免疫性疾病发病情况、患者一级亲属患病情况等。结果978例白癜风患者中，有家族史患者174例（17.8%）；有家族史患者平均发病年龄早于无家族史患者，平均病程长于无家族史患者（P＜0.05）；白癜风患者类风湿关节炎、慢性荨麻疹、斑秃、银屑病患病率均高于普通人群；白癜风患者一级亲属中类风湿关节炎、慢性荨麻疹、斑秃患病率均高于普通人群；有家族史患者甲状腺功能亢进症、慢性荨麻疹、斑秃、银屑病患病率高于无家族史患者（P＜0.05）。结论遗传因素及自身免疫因素与白癜风的发病有一定关系，白癜风可能与某些自身免疫性疾病有共同的发病基础。
目的：調查分析白癜風患病人群常見相關自身免疫性疾病的患病情況，為白癜風患病人群自身免疫性疾病的防治提供參攷。方法選取2007年1月至2014年5月于本院皮膚科就診的978例白癜風患者為研究對象。經患者知情同意後，採用自行設計的調查問捲對入選患者進行流行病學調查，調查主要內容包括：患者基本情況、髮病年齡、髮病部位、自身免疫性疾病髮病情況、患者一級親屬患病情況等。結果978例白癜風患者中，有傢族史患者174例（17.8%）；有傢族史患者平均髮病年齡早于無傢族史患者，平均病程長于無傢族史患者（P＜0.05）；白癜風患者類風濕關節炎、慢性蕁痳疹、斑禿、銀屑病患病率均高于普通人群；白癜風患者一級親屬中類風濕關節炎、慢性蕁痳疹、斑禿患病率均高于普通人群；有傢族史患者甲狀腺功能亢進癥、慢性蕁痳疹、斑禿、銀屑病患病率高于無傢族史患者（P＜0.05）。結論遺傳因素及自身免疫因素與白癜風的髮病有一定關繫，白癜風可能與某些自身免疫性疾病有共同的髮病基礎。
목적：조사분석백전풍환병인군상견상관자신면역성질병적환병정황，위백전풍환병인군자신면역성질병적방치제공삼고。방법선취2007년1월지2014년5월우본원피부과취진적978례백전풍환자위연구대상。경환자지정동의후，채용자행설계적조사문권대입선환자진행류행병학조사，조사주요내용포괄：환자기본정황、발병년령、발병부위、자신면역성질병발병정황、환자일급친속환병정황등。결과978례백전풍환자중，유가족사환자174례（17.8%）；유가족사환자평균발병년령조우무가족사환자，평균병정장우무가족사환자（P＜0.05）；백전풍환자류풍습관절염、만성담마진、반독、은설병환병솔균고우보통인군；백전풍환자일급친속중류풍습관절염、만성담마진、반독환병솔균고우보통인군；유가족사환자갑상선공능항진증、만성담마진、반독、은설병환병솔고우무가족사환자（P＜0.05）。결론유전인소급자신면역인소여백전풍적발병유일정관계，백전풍가능여모사자신면역성질병유공동적발병기출。
ObjectiveTo analyze the common autoimmune diseases in patients with vitiligo and to provide for the prevention and treatment of autoimmune diseases.Method978 patients with vitiligo from January 2007 to May 2014 in our hospital were selected as the research objects. The self-designed questionnaires were adopt for patients. The basic situation, age, autoimmune disease, infection situation and the disease of ifrst degree relative were surveyed.Result174 patients had the family history in 978 cases of vitiligo patients, accounted for 17.8%. The average age onset of patients with family history were earlier than patients without family history and the average duration were longer than patients without family history. The incidence of rheumatoid arthritis, chronic urticaria, alopecia areata and psoriasis of patients with vitiligo were higher than common people. The incidence of rheumatoid arthritis, chronic urticaria, alopecia areata of ifrst degree relative with vitiligo were higher than common people. The incidence of hyperthyroidism, chronic urticaria, alopecia areata and psoriasis of patients with family history was higher than patients without family history (P<0.05). ConclusionGenetic factors and immune factors play an important role in the vitiligo. The vitiligo may have a common basis with certain autoimmune diseases.
