中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
Chinese Journal of Clinical Nutrition
2015年
4期
214-218
,共5页
林莹%杨军红%陈颖新%李萍%安冬%赵文卓%田曦
林瑩%楊軍紅%陳穎新%李萍%安鼕%趙文卓%田晞
림형%양군홍%진영신%리평%안동%조문탁%전희
米油%急性腹泻%儿童%分泌型免疫球蛋白A%呕吐
米油%急性腹瀉%兒童%分泌型免疫毬蛋白A%嘔吐
미유%급성복사%인동%분비형면역구단백A%구토
Rice oil%Acute diarrhea%Children%Secretory immunoglobulin A%Vomit
目的 研究米油对急性腹泻患儿大便中分泌型免疫球蛋白A (sIgA)含量及疾病转归的影响.方法 选取2013年1月至2014年10月天津市儿童医院住院的急性腹泻患儿180例.采用随机数码表法随机分为米油组、蒙脱石散组与对照组,每组60例.观察并比较3组患儿的疗效,腹泻、呕吐消退时间,住院时间及治疗前后大便sIgA含量.结果 米油组及蒙脱石散组治疗总有效率(93.3％、96.7％)显著高于对照组(76.7％,P=0.011、0.001);米油组及蒙脱石散组住院时间、腹泻消退时间、呕吐消退时间显著短于对照组[(5.6±1.4)、(5.7±1.6)d比(6.9±1.8)d;(3.7±0.9)、(3.5±0.9)d比(5.4±1.2)d;(2.8±0.6)、(3.2±0.8)d比(5.1±0.8)d;均P=0.000];米油组治疗总有效率、住院时间、腹泻消退时间与蒙脱石散组比较差异无统计学意义(P =0.402、0.716、0.226),呕吐消退时间显著短于蒙脱石散组(P=0.016).治疗前对照组、蒙脱石散组、米油组大便sIgA分别为0.527±0.133、0.487 ±0.109、0.534±0.150,3组间差异无统计学意义(P＞0.05).治疗后第2天,米油组、蒙脱石散组大便中sIgA (0.669±0.176、0.612±0.161)显著高于对照组(0.541±0.149) (P=0.000、0.014),蒙脱石散组与米油组差异无统计学意义(P=0.067);治疗后第4天,蒙脱石散组sIgA (1.981 ±0.462)显著高于对照组(1.762±0.378) (P =0.005),米油组sIgA(2.331±0.494)显著高于其他两组(P=0.000).治疗后第2天与治疗前相比,对照组sIgA变化差异无统计学意义(P=0.295),蒙脱石散组及米油组sIgA均显著性升高(均P=0.000);治疗后第4天与治疗后第2天相比,3组sIgA均显著性升高(均P=0.000).结论 米油治疗儿童急性腹泻疗效与蒙脱石散相同,对治疗呕吐及促进肠道sIgA分泌效果更优.
目的 研究米油對急性腹瀉患兒大便中分泌型免疫毬蛋白A (sIgA)含量及疾病轉歸的影響.方法 選取2013年1月至2014年10月天津市兒童醫院住院的急性腹瀉患兒180例.採用隨機數碼錶法隨機分為米油組、矇脫石散組與對照組,每組60例.觀察併比較3組患兒的療效,腹瀉、嘔吐消退時間,住院時間及治療前後大便sIgA含量.結果 米油組及矇脫石散組治療總有效率(93.3％、96.7％)顯著高于對照組(76.7％,P=0.011、0.001);米油組及矇脫石散組住院時間、腹瀉消退時間、嘔吐消退時間顯著短于對照組[(5.6±1.4)、(5.7±1.6)d比(6.9±1.8)d;(3.7±0.9)、(3.5±0.9)d比(5.4±1.2)d;(2.8±0.6)、(3.2±0.8)d比(5.1±0.8)d;均P=0.000];米油組治療總有效率、住院時間、腹瀉消退時間與矇脫石散組比較差異無統計學意義(P =0.402、0.716、0.226),嘔吐消退時間顯著短于矇脫石散組(P=0.016).治療前對照組、矇脫石散組、米油組大便sIgA分彆為0.527±0.133、0.487 ±0.109、0.534±0.150,3組間差異無統計學意義(P＞0.05).治療後第2天,米油組、矇脫石散組大便中sIgA (0.669±0.176、0.612±0.161)顯著高于對照組(0.541±0.149) (P=0.000、0.014),矇脫石散組與米油組差異無統計學意義(P=0.067);治療後第4天,矇脫石散組sIgA (1.981 ±0.462)顯著高于對照組(1.762±0.378) (P =0.005),米油組sIgA(2.331±0.494)顯著高于其他兩組(P=0.000).治療後第2天與治療前相比,對照組sIgA變化差異無統計學意義(P=0.295),矇脫石散組及米油組sIgA均顯著性升高(均P=0.000);治療後第4天與治療後第2天相比,3組sIgA均顯著性升高(均P=0.000).結論 米油治療兒童急性腹瀉療效與矇脫石散相同,對治療嘔吐及促進腸道sIgA分泌效果更優.
목적 연구미유대급성복사환인대편중분비형면역구단백A (sIgA)함량급질병전귀적영향.방법 선취2013년1월지2014년10월천진시인동의원주원적급성복사환인180례.채용수궤수마표법수궤분위미유조、몽탈석산조여대조조,매조60례.관찰병비교3조환인적료효,복사、구토소퇴시간,주원시간급치료전후대편sIgA함량.결과 미유조급몽탈석산조치료총유효솔(93.3％、96.7％)현저고우대조조(76.7％,P=0.011、0.001);미유조급몽탈석산조주원시간、복사소퇴시간、구토소퇴시간현저단우대조조[(5.6±1.4)、(5.7±1.6)d비(6.9±1.8)d;(3.7±0.9)、(3.5±0.9)d비(5.4±1.2)d;(2.8±0.6)、(3.2±0.8)d비(5.1±0.8)d;균P=0.000];미유조치료총유효솔、주원시간、복사소퇴시간여몽탈석산조비교차이무통계학의의(P =0.402、0.716、0.226),구토소퇴시간현저단우몽탈석산조(P=0.016).치료전대조조、몽탈석산조、미유조대편sIgA분별위0.527±0.133、0.487 ±0.109、0.534±0.150,3조간차이무통계학의의(P＞0.05).치료후제2천,미유조、몽탈석산조대편중sIgA (0.669±0.176、0.612±0.161)현저고우대조조(0.541±0.149) (P=0.000、0.014),몽탈석산조여미유조차이무통계학의의(P=0.067);치료후제4천,몽탈석산조sIgA (1.981 ±0.462)현저고우대조조(1.762±0.378) (P =0.005),미유조sIgA(2.331±0.494)현저고우기타량조(P=0.000).치료후제2천여치료전상비,대조조sIgA변화차이무통계학의의(P=0.295),몽탈석산조급미유조sIgA균현저성승고(균P=0.000);치료후제4천여치료후제2천상비,3조sIgA균현저성승고(균P=0.000).결론 미유치료인동급성복사료효여몽탈석산상동,대치료구토급촉진장도sIgA분비효과경우.
Objective To study the effect of rice oil on secretory immunoglobulin A (sIgA) content in feces and disease outcome in children with acute diarrhea.Methods We selected 180 children with acute diarrhea hospitalized in Tianjin Children's Hospital during the period from January 2013 to October 2014.They were randomly divided with a random number table into rice oil group,montmorillonite powder group and control group (all n =60).The effect of treatment,duration before subsiding of diarrhea and vomit,length of hospital stay and sIgA content in feces before and after treatment were analyzed.Results The total effective rates in the rice oil group and the montmorillonite powder group (93.3％,96.7％) were significantly higher than that in the control group (76.7％,P =0.011,P =0.001).Length of hospital stay,duration before subsiding of diarrhea and vomit in the rice oil group and the montmorillonite powder group were significantly shorter than those in the control group[(5.6±1.4) d,(5.7±1.6) d vs.(6.9±1.8) d;(3.7±0.9) d,(3.5±0.9) d vs.(5.4±1.2) d;(2.8 ± 0.6) d,(3.2 ± 0.8) d vs.(5.1 ± 0.8) d;all P =0.000].The total effective rates,length of hospital stay,duration before subsiding of diarrhea showed no statistically significant differences between the rice oil group and the montmorillonite powder group (P =0.402,0.716,0.226),but the duration before subsiding of vomit in the rice oil group was significantly shorter than that in the montmorillonite powder group (P =0.016).Before treatment,the sIgA contents in feces in the control group,the montmorillonite powder group,the rice oil group were 0.527 ± 0.133,0.487 ± 0.109,0.534 ± 0.150,with no significant difference (P ＞ 0.05).Two days after treatment,sIgA contents in the rice oil group and the montmorillonite powder group (0.669 ±0.176,0.612 ± 0.161) were significantly higher than in the control group (0.541 ±0.149,P =0.000,0.014).There was no significant difference between the montmorillonite powder group and the rice oil group (P =0.067).Four days after treatment,sIgA content in the montmorillonite powder group (1.981 ±0.462) was significantly higher than in the control group (1.762 ±0.378,P =0.005),while sIgA content in the rice oil group (2.331 ± 0.494) was significantly higher than in the other 2 groups (P =0.000).Compared with the levels before treatment,sIgA content 2 days after treatment was not significantly changed in the control group (P =0.295),but was significantly elevated in the montmorillonite powder group and the rice oil group (both P =0.000).sIgA contents of all the three groups 4 days after treatment were significantly higher than the contents 2 days after treatment (all P =0.000).Conclusion The effect of rice oil on acute diarrhea in children is as same as that of montmorillonite powder,and may be better in mitigating vomit and promoting the secretion of intestinal sIgA.
