CAJ | 학술논문

目的：探讨18F-FDG PET-CT显像在妇科恶性肿瘤复发中的临床应用价值。方法：选取经过本院确诊的30例妇科恶性肿瘤患者，分为两组，第一组10例，治疗后采取18F-FDG PET-CT显像检查有无肿瘤复发现象；第二组20例，临床上已经被怀疑存在肿瘤复发情况，利用18F-FDG PET-CT显像技术进行明确诊断。探讨18F-FDG PET-CT显像在妇科肿瘤复发中的临床应用价值。结果：第一组中有8例患者在治疗后首次进行18F-FDG PET-CT显像检查结果呈阴性，其中1例患者在半年后再次进行18F-FDG PET-CT显像呈阳性，经过检查以及手术证实为消化系统癌症；另外2例患者18F-FDG PET-CT显像结果虽然为阳性，但是经过检查并未发现有肿瘤复发的现象，且至今身体状况良好，所以考虑术后改变导致的18F-FDG PET-CT结果呈现假阳性。第二组中15例患者的18F-FDG PET-CT显像结果呈阳性，其中3例经过手术病理证实为肿瘤复发；而另外12例给予化疗或放疗措施，其中7例患者的肿瘤病灶缩小，2例患者因为治疗无效而死亡，3例患者的病灶并无明显的变化；5例患者的18F-FDG PET-CT显像结果为阴性，其中2例再次进行18F-FDG PET-CT检查时结果为阳性，经手术证实为肿瘤复发，另外3例患者至今没有发现复发现象。结论：18F-FDG PET-CT显像对妇科恶性肿瘤的复发可以及时诊断出来，从而可以对复发患者进行及时而针对性的治疗，降低患者的痛苦以及死亡率，18F-FDG PET-CT显像是一种有效的方法，对于在临床治疗肿瘤方面制定和调整方案有着重要的意义。
목적：탐토18F-FDG PET-CT현상재부과악성종류복발중적림상응용개치。방법：선취경과본원학진적30례부과악성종류환자，분위량조，제일조10례，치료후채취18F-FDG PET-CT현상검사유무종류복발현상；제이조20례，림상상이경피부의존재종류복발정황，이용18F-FDG PET-CT현상기술진행명학진단。탐토18F-FDG PET-CT현상재부과종류복발중적림상응용개치。결과：제일조중유8례환자재치료후수차진행18F-FDG PET-CT현상검사결과정음성，기중1례환자재반년후재차진행18F-FDG PET-CT현상정양성，경과검사이급수술증실위소화계통암증；령외2례환자18F-FDG PET-CT현상결과수연위양성，단시경과검사병미발현유종류복발적현상，차지금신체상황량호，소이고필술후개변도치적18F-FDG PET-CT결과정현가양성。제이조중15례환자적18F-FDG PET-CT현상결과정양성，기중3례경과수술병리증실위종류복발；이령외12례급여화료혹방료조시，기중7례환자적종류병조축소，2례환자인위치료무효이사망，3례환자적병조병무명현적변화；5례환자적18F-FDG PET-CT현상결과위음성，기중2례재차진행18F-FDG PET-CT검사시결과위양성，경수술증실위종류복발，령외3례환자지금몰유발현복발현상。결론：18F-FDG PET-CT현상대부과악성종류적복발가이급시진단출래，종이가이대복발환자진행급시이침대성적치료，강저환자적통고이급사망솔，18F-FDG PET-CT현상시일충유효적방법，대우재림상치료종류방면제정화조정방안유착중요적의의。
Objective: To evaluate application value of18F-FDG PET-CT in diagnosing recurrent gynecologic carcinoma.Method: We chose 30 patients with gynecologic carcinoma after diagnosing and divided these patients into two groups. The first group contained 10 cases, they underwent the18F-FDG PET-CT to examine the recurrent carcinoma after treatment. The second group contained 20 cases, and they were suspicious of recurrence in the clinic and they underwent the18F-FDG PET-CT.Result: In the first group, there were 8 cases were negative results after undergoing the18F-FDG PET-CT, including 1 case was positive result when undergoing the second18F-FDG PET-CT examine, and proved to be digestive system cancer, 2 cases with positive result were diagnosed post-treatment changes. In the second group, 15 cases were positive results and 3 cases were proved to recurrent or move by operation, and the other 12 cases were given chemotherapy or radiotherapy, then 7 patients’ recurrent tumor volume reduced, and 2 cases died, 3 patients’ tumor had no change. The other 5 cases were negative results, but 2 cases changed to be positive results after the second examination and proved to be recurrent carcinoma.Conclusion: The18F-FDG PET-CT examination is helpful to diagnose and treat the recurrent carcinoma earlier. It can reduce the pain of the patients and mortality, it is an effective method of monitoring of gynecologic carcinoma recurrence, and has important clinical significance to formulate and adjust the treatment plan in the clinic.