中外医学研究
中外醫學研究
중외의학연구
Chinese and Foreign Medical Research
2015年
27期
3-5
,共3页
肝硬化%上消化道出血%奥曲肽%埃索美拉唑
肝硬化%上消化道齣血%奧麯肽%埃索美拉唑
간경화%상소화도출혈%오곡태%애색미랍서
Liver cirrhosis%Upper gastrointestinal hemorrhage%Octreotide%Esomeprazole
目的：探讨奥曲肽联合埃索美拉唑治疗肝硬化上消化道出血的临床疗效。方法：选取2012年2月-2015年2月苏州相城人民医院收治的肝硬化并发上消化道出血69例患者，随机分为对照组(n=34)和试验组(n=35)，两组患者均给予补充血容量和一般性止血药等基础治疗，在此基础上对照组静脉滴注奥曲肽，试验组静脉滴注奥曲肽联合埃索美拉唑，观察两组患者的临床疗效。结果：与对照组相比，试验组患者的总有效率显著高，平均住院时间和不良反应率均显著低，两组比较差异均有统计学意义(P<0.05)。结论：奥曲肽联合埃索美拉唑治疗肝硬化合并上消化道出血，临床效果确切，值得临床上加以推广应用。
目的：探討奧麯肽聯閤埃索美拉唑治療肝硬化上消化道齣血的臨床療效。方法：選取2012年2月-2015年2月囌州相城人民醫院收治的肝硬化併髮上消化道齣血69例患者，隨機分為對照組(n=34)和試驗組(n=35)，兩組患者均給予補充血容量和一般性止血藥等基礎治療，在此基礎上對照組靜脈滴註奧麯肽，試驗組靜脈滴註奧麯肽聯閤埃索美拉唑，觀察兩組患者的臨床療效。結果：與對照組相比，試驗組患者的總有效率顯著高，平均住院時間和不良反應率均顯著低，兩組比較差異均有統計學意義(P<0.05)。結論：奧麯肽聯閤埃索美拉唑治療肝硬化閤併上消化道齣血，臨床效果確切，值得臨床上加以推廣應用。
목적：탐토오곡태연합애색미랍서치료간경화상소화도출혈적림상료효。방법：선취2012년2월-2015년2월소주상성인민의원수치적간경화병발상소화도출혈69례환자，수궤분위대조조(n=34)화시험조(n=35)，량조환자균급여보충혈용량화일반성지혈약등기출치료，재차기출상대조조정맥적주오곡태，시험조정맥적주오곡태연합애색미랍서，관찰량조환자적림상료효。결과：여대조조상비，시험조환자적총유효솔현저고，평균주원시간화불량반응솔균현저저，량조비교차이균유통계학의의(P<0.05)。결론：오곡태연합애색미랍서치료간경화합병상소화도출혈，림상효과학절，치득림상상가이추엄응용。
Objective:To investigate the effect of Octreotide combined with Esomeprazole in the treatment of liver cirrhosis with upper gastrointestinal hemorrhage.Method:69 patients with liver cirrhosis complicated with upper gastrointestinal hemorrhage were enrolled into this clinical trial from February 2012 to February 2015 at Suzhou Xiangcheng People’s Hospital,which were randomized into the control group(n=34) and test group(n=35) that were treated intravenously with octreotide alone and Octreotide combined with Esomeprazole following the basic treatment respectively. Result:Compared to the control group,a significant increase in total efficacy rate,a significant decrease in mean hospitalization time and a significant decrease in adverse reactions were observed for the test group,the differences were statistically significant(P<0.05).Conclusion:It is concluded that Octreotide combined with Esomeprazole are beneficial in the treatment of liver cirrhosis complicated with upper gastrointestinal hemorrhage.
