现代临床医学
現代臨床醫學
현대림상의학
Journal of Modern Clinical Medicine
2015年
5期
372-373
,共2页
可逆性后部白质脑病综合征%CT%MRI
可逆性後部白質腦病綜閤徵%CT%MRI
가역성후부백질뇌병종합정%CT%MRI
reversible posterior leukoencephalopathy syndrome%computed tomography%magnetic resonance imaging
目的：分析和总结可逆性后部白质脑病综合征（ reversible posterior leukoencephalopathy syndrome，RPLS）的CT、MRI表现，提高对此种疾病的认识水平。方法：回顾8例经临床、影像学及其治疗结果证实的RPLS的CT、MRI的影像学特点。结果：8例RPLS中，双侧枕顶叶白质均可见病灶，2例累及额颞叶，1例累及基底节，1例累及左小脑区。5例CT均表现为片状低密度，边界不清；MRI所有病例T1WI序列为低信号，T2WI、FLAIR为高信号，3例DWI为等或稍低信号，1例DWI为稍高信号。所有病例治疗短期（10～15 d）复查均见病灶吸收消失或明显缩小。结论：RPLS在CT、MRI上有一定的特点，尤其是MRI，表现为枕顶叶白质为主对称性发病，DWI等或稍低信号，ADC图高信号，结合临床病史、症状、体征，可以作出准确诊断。
目的：分析和總結可逆性後部白質腦病綜閤徵（ reversible posterior leukoencephalopathy syndrome，RPLS）的CT、MRI錶現，提高對此種疾病的認識水平。方法：迴顧8例經臨床、影像學及其治療結果證實的RPLS的CT、MRI的影像學特點。結果：8例RPLS中，雙側枕頂葉白質均可見病竈，2例纍及額顳葉，1例纍及基底節，1例纍及左小腦區。5例CT均錶現為片狀低密度，邊界不清；MRI所有病例T1WI序列為低信號，T2WI、FLAIR為高信號，3例DWI為等或稍低信號，1例DWI為稍高信號。所有病例治療短期（10～15 d）複查均見病竈吸收消失或明顯縮小。結論：RPLS在CT、MRI上有一定的特點，尤其是MRI，錶現為枕頂葉白質為主對稱性髮病，DWI等或稍低信號，ADC圖高信號，結閤臨床病史、癥狀、體徵，可以作齣準確診斷。
목적：분석화총결가역성후부백질뇌병종합정（ reversible posterior leukoencephalopathy syndrome，RPLS）적CT、MRI표현，제고대차충질병적인식수평。방법：회고8례경림상、영상학급기치료결과증실적RPLS적CT、MRI적영상학특점。결과：8례RPLS중，쌍측침정협백질균가견병조，2례루급액섭협，1례루급기저절，1례루급좌소뇌구。5례CT균표현위편상저밀도，변계불청；MRI소유병례T1WI서렬위저신호，T2WI、FLAIR위고신호，3례DWI위등혹초저신호，1례DWI위초고신호。소유병례치료단기（10～15 d）복사균견병조흡수소실혹명현축소。결론：RPLS재CT、MRI상유일정적특점，우기시MRI，표현위침정협백질위주대칭성발병，DWI등혹초저신호，ADC도고신호，결합림상병사、증상、체정，가이작출준학진단。
Objective:To analyze the manifestations of reversible posterior leukoencephalopathy syndrome( RPLS) in CT and MRI, to improve the understanding of this disease.Methods:CT and MRI imaging characteristics of the 8 patients were analyzed , who were confirmed to RPLS by clinical,imaging and treatment outcome of in the past two years.Results:The both bilateral occipital subeortieal white matter were affected in 8 cases of RPLS, frontal temporal lobe in 2 patient,basal ganglia in 1 patient,the left cerebellum area in 1 patient.CT manifestations of 5 patients were low density flake,were not clear boundary;in all the cases,lesions appeard as hyperintense signals on FLAIR and T2 -weighted images, hypointense signals on T1 -weighted images;iso-intensity or slight low-intensity signal on DWI in 3 cases,slightly hyper-intensity signal on DWI in 1 cases.All cases of short -term treatment ( 10 ~15 days ) were reviewed in lesions absorption which were disappeared or significantly narrowed.Conclusion:RPLS have certain CT and MRI characteristics,especially MRI;the lesion mainly symmetrically happenin the white matter of the pillow parietal, iso-intensity or slight low-intensity signal on DWI, hyper-intensity signal on ADC,and are combined with the clinical history, symptoms,signs,we can make an accurate diagnosis.
