CAJ | 학술논문

目的：观察运用免疫因子联合疗法治疗免疫性甲状腺疾病的临床疗效。方法：严格按照纳入标准将116例自身免疫性甲状腺疾病患者随机分2组，治疗组58例，对照组58例。采用免疫因子联合疗法治疗，采用常规抗甲状腺药物治疗。两组疗程均为3个月。观察患者治疗前后临床症状、体征和实验室化验、检查指标变化。结果：①两组患者治疗后有效率分别是98.3%和53.4%，临床治愈率分别是94.8%和43.1%，治疗组明显优于对照组，且差异性有统计学意义(P＜0.05)。②免疫因子联合疗法治疗后甲状腺抗体下降(P＜0.05)③免疫因子联合疗法治疗后可改善和消除免疫性甲状腺疾病各种临床症状、体征，治疗组优于对照组。结论：两组治疗方法对免疫性甲状腺疾病都有一定的改善作用，但治疗组总有效率和治愈率明显优于对照组。说明免疫因子联合疗法治疗免疫性甲状腺疾病疗效更佳。
목적：관찰운용면역인자연합요법치료면역성갑상선질병적림상료효。방법：엄격안조납입표준장116례자신면역성갑상선질병환자수궤분2조，치료조58례，대조조58례。채용면역인자연합요법치료，채용상규항갑상선약물치료。량조료정균위3개월。관찰환자치료전후림상증상、체정화실험실화험、검사지표변화。결과：①량조환자치료후유효솔분별시98.3%화53.4%，림상치유솔분별시94.8%화43.1%，치료조명현우우대조조，차차이성유통계학의의(P＜0.05)。②면역인자연합요법치료후갑상선항체하강(P＜0.05)③면역인자연합요법치료후가개선화소제면역성갑상선질병각충림상증상、체정，치료조우우대조조。결론：량조치료방법대면역성갑상선질병도유일정적개선작용，단치료조총유효솔화치유솔명현우우대조조。설명면역인자연합요법치료면역성갑상선질병료효경가。
Objective: To investigate the combination therapy of immune factors for autoimmune thyroid disease. Methods: 116 patients with autoimmune thyroid disease were randomly divided into two groups, 58 cases for each. The combined therapy was given to the treatment group, and the conventional antithyroid treatment was given to control group. Clinical symptoms, signs and laboratory tests before and after treatment were recorded. Results:①After treatment the efficiency were 98.3% and 53.4%,clinical efficacy were 94.8% and 43.1% in the treatment group than the control group, and the difference was statistically significant (P<0.05).② with immune factors combination therapy, thyroid antibody decreased (P<0.05).③immune factors in combination therapy can improve and eliminate all kinds of clinical symptoms, signs in autoimmune thyroid disease, more in the treatment group than the control group. Conclusion: Immune factors combination therapy for autoimmune thyroid disease show better effect.