CAJ | 학술논문

目的：对危重症合并急性肾衰竭患者采用连续性血液滤过联合血液灌流治疗，观察和分析其治疗效果。方法：将116例病例按照住院先后顺序分为对照组和治疗组。对照组采用常规方法治疗，治疗组在对照组治疗基础上采用连续性血液滤过联合血液灌流治疗。结果：2组患者治疗前APACHEⅡ评分比较无显著性差异（P＞0.05）；治疗后，24 h、48 h、72 h的APACHEⅡ评分均下降，与治疗前比较有显著性差异（P＜0.05），治疗组优于对照组（P＜0.05）。治疗后2组血清BUN和Scr、TBIL等均明显下降，且治疗组优于对照组；治疗组死亡率为3.45％，明显低于对照组的13.79％（ P＜0.05）。结论：采用连续性血液滤过联合血液灌流治疗危重症合并急性肾衰竭患者，可清除细胞因子，降低死亡率。
목적：대위중증합병급성신쇠갈환자채용련속성혈액려과연합혈액관류치료，관찰화분석기치료효과。방법：장116례병례안조주원선후순서분위대조조화치료조。대조조채용상규방법치료，치료조재대조조치료기출상채용련속성혈액려과연합혈액관류치료。결과：2조환자치료전APACHEⅡ평분비교무현저성차이（P＞0.05）；치료후，24 h、48 h、72 h적APACHEⅡ평분균하강，여치료전비교유현저성차이（P＜0.05），치료조우우대조조（P＜0.05）。치료후2조혈청BUN화Scr、TBIL등균명현하강，차치료조우우대조조；치료조사망솔위3.45％，명현저우대조조적13.79％（ P＜0.05）。결론：채용련속성혈액려과연합혈액관류치료위중증합병급성신쇠갈환자，가청제세포인자，강저사망솔。
Objective:To observe the effect of continuous hemofiltration combined with blood perfusion in treatment of critical patients with acute renal failure.Methods:116 patients were divided into control group and treatment group.Control group:only had basis conventional treatment.Treatment group:had continuous hemofiltration combined with blood perfusion therapy in addition to basis.Results:APACHEⅡ score had no difference before treatment in both groups ( P >0.05 );After treatment,24 h,48 h,72 h APACHEⅡscore were decreased, compared with before treatment( P<0.05) in both groups;But the treatment group was better than that of control group( P<0.05).In both groups the serum BUN and Scr,TBIL were significantly decreased after treatment,but in the treatment group was better than in the control group;3.45%mortality in treatment group was obviouslylower than 13.79% in the control group ( P <0.05 ).Conclusion:Continuous hemofiltration combined with blood perfusion for critical patients with acute renal failure can clear cytokines, reduce mortality.