CAJ | 학술논문

目的：探讨食管覆膜支架置入联合放射治疗对中晚期食管癌治疗的临床价值。方法对35例中晚期食管癌患者进行覆膜支架置入术并放射治疗(治疗组),对37例中晚期食管癌患者进行单纯放射治疗(对照组),并进行临床疗效对比观察。结果治疗组术后患者吞咽困难症状均明显缓解,坚持完成全程放射治疗32例(91.4%),无因营养状况原因导致治疗情况不能完成；放射治疗后1个月以上生存期达100.0%,6个月生存期为85.7%(30/35)。对照组放射治疗开始1周内吞咽困难症状加重或无缓解,需静脉营养支持；完成全程放射治疗23例(62.2%),发生食管气管瘘5例；放射治疗后1个月生存期为83.8%(31/37),6个月生存期为62.2%(23/37)。两组患者放射治疗耐受性及放射治疗后1、6个月生存期差异有统计学意义(均 P <0.05)。结论对中晚期食管癌患者,予以食管覆膜支架置入联合放射治疗较单纯放射治疗有较好疗效。
목적：탐토식관복막지가치입연합방사치료대중만기식관암치료적림상개치。방법대35례중만기식관암환자진행복막지가치입술병방사치료(치료조),대37례중만기식관암환자진행단순방사치료(대조조),병진행림상료효대비관찰。결과치료조술후환자탄인곤난증상균명현완해,견지완성전정방사치료32례(91.4%),무인영양상황원인도치치료정황불능완성；방사치료후1개월이상생존기체100.0%,6개월생존기위85.7%(30/35)。대조조방사치료개시1주내탄인곤난증상가중혹무완해,수정맥영양지지；완성전정방사치료23례(62.2%),발생식관기관루5례；방사치료후1개월생존기위83.8%(31/37),6개월생존기위62.2%(23/37)。량조환자방사치료내수성급방사치료후1、6개월생존기차이유통계학의의(균 P <0.05)。결론대중만기식관암환자,여이식관복막지가치입연합방사치료교단순방사치료유교호료효。
Objective To study the clinical value of esophageal stent placement with radiation therapy for the middle-late pa-tients with esophageal cancer.Methods To perform esophageal stent placement and radiation therapy for the middle-late 35 pa-tients,and to perform radiation therapy for the middle-late 37 patients,then observe the clinical curative effects.Results The treat-ment group were significantly alleviated with dysphagia symptom after operation,which 32 cases sticked the entire radiation,ac-counting for 91.4%,no one can′t complete the treatment because of nutritional status reason.Survival time of one month after ra-diotherapy was up to 100.0%,and survival time of six months was 85.7% (30/35).But the contrast group with dysphagia symp-tom were aggravated or no relief,and needed parenteral nutrition.There were 23 cases to complete the entire radiation,accounting for 62.2%,and 5 cases happened esophageal tracheal fistula.Survival time of one month after radiotherapy was 83.8%(31/37),and survival time of six months was 62.2% (23/37).Two groups of cases in radiotherapy resistance difference was statistically signifi-cant,one month and six months of survival time were statistically significant (all P <0.05 ).Conclusion Esophageal stent place-ment with radiotherapy is more efficient than only radiation therapy to the middle-late patients with esophageal cancer.