CAJ | 학술논문

目的：探讨二地鳖甲煎联合小剂量他达拉非治疗糖尿病性勃起功能障碍（DED）的临床疗效。方法选取70例 DED 患者，随机将其分为治疗组和对照组各35例，治疗组给予二地鳖甲煎汤剂每日1剂，分早晚2次口服，他达拉非片5 mg 每晚1次口服，连续使用8周；对照组口服他达拉非片5 mg 每晚1次，连续服用8周。治疗前后进行 IIEF？5评分以及夜间阴茎勃起检查。结果2组治疗后 IIEF？5评分以及夜间阴茎勃起检查结果均有显著提高（P ＜0．01），治疗后治疗组优于对照组（P ＜0．05）。2组均未出现严重不良反应。结论二地鳖甲煎联合小剂量他达拉非治疗 DED 安全有效，值得临床推广。
목적：탐토이지별갑전연합소제량타체랍비치료당뇨병성발기공능장애（DED）적림상료효。방법선취70례 DED 환자，수궤장기분위치료조화대조조각35례，치료조급여이지별갑전탕제매일1제，분조만2차구복，타체랍비편5 mg 매만1차구복，련속사용8주；대조조구복타체랍비편5 mg 매만1차，련속복용8주。치료전후진행 IIEF？5평분이급야간음경발기검사。결과2조치료후 IIEF？5평분이급야간음경발기검사결과균유현저제고（P ＜0．01），치료후치료조우우대조조（P ＜0．05）。2조균미출현엄중불량반응。결론이지별갑전연합소제량타체랍비치료 DED 안전유효，치득림상추엄。
ABSTRACTOBJECTIVE To discuss the clinical effect of Erdi Biejia decoction together with low dose of Tadalafil in treating diabetic erectile dysfunction.METHODS 70 patients with DED were randomly divided into two groupsthe control group35 cases and the treatment group35 cases.The treatment group was given Erdi Biejia decoction one dosage every dayorally taken in the morning and evening.Tadalafil pills5mg were orally taken once every night for eight weeks.The control group took Tadalafil pills5mg once every night for eight weeks.Before and after the treatmentIIEF?5 scores and nocturnal penile tumescence were recorded.RESULTS After the treatmentIIEF?5 scores and nocturnal penile tumescence of both groups sig-nificantly improvedP <0.01.After the treatmentthe treatment group performed better than the control groupP <0.05. So serious side effects showed in the two groups.CONCLUSION Erdi Biejia decoction together with low dose of Tadalafil were effective in treating DED and were worth of being widely applied in clinical practices.