CAJ | 학술논문

目的：回顾分析77例溃疡性结肠炎(UC)患者的临床资料和随访情况以指导并完善 UC 的诊治。方法收集该院2009年11月至2014年10月住院治疗的77例 UC 患者临床资料并电话随访一部分患者维持治疗情况。结果活动期 UC 患者中度活动者占69.9%,病变范围以左半结肠(46.6%,34/73)及广泛结肠(50.7%,37/73)为主。UC 主要临床表现为腹痛、腹泻、黏液脓血便及便血等。肠镜下 UC 活动期主要表现为肠黏膜充血、肿胀、糜烂及浅溃疡形成,内镜下组织活检多表现为黏膜慢性炎症和(或)糜烂。UC 患者病情越重,相对应的血清清蛋白平均值越低。治疗上以氨基水杨酸制剂、糖皮质激素及免疫抑制剂为主。氨基水杨酸制剂是长期维持治疗药物,UC 总体治疗有效率为89.0%(55/73)。结论UC 治疗方案基本遵循共识意见,仍需加强 UC 随访。
목적：회고분석77례궤양성결장염(UC)환자적림상자료화수방정황이지도병완선 UC 적진치。방법수집해원2009년11월지2014년10월주원치료적77례 UC 환자림상자료병전화수방일부분환자유지치료정황。결과활동기 UC 환자중도활동자점69.9%,병변범위이좌반결장(46.6%,34/73)급엄범결장(50.7%,37/73)위주。UC 주요림상표현위복통、복사、점액농혈편급편혈등。장경하 UC 활동기주요표현위장점막충혈、종창、미란급천궤양형성,내경하조직활검다표현위점막만성염증화(혹)미란。UC 환자병정월중,상대응적혈청청단백평균치월저。치료상이안기수양산제제、당피질격소급면역억제제위주。안기수양산제제시장기유지치료약물,UC 총체치료유효솔위89.0%(55/73)。결론UC 치료방안기본준순공식의견,잉수가강 UC 수방。
Objective To analyze the clinical characteristics,therapy and follow-up of the patients with ulcerative colitis (UC).Methods Collect the date of 77 inpatients with UC at the Second Affiliated Hospital of Chongqing Medical University be-tween November,2009 and october,2014,and assigned the patients randomly.Results 69.9% of the patients who were in the ac-tivity stage were moderate severity.E2 (46.6%,34/73)and E3 (50.7%,37/73)were the common lesions range.The main clinical manifestations were abdominal pain,diarrhea,mucopurulent bloody stool and bloody stool.The enteroscopy mostly showed that in-testinal mucosa hyperemia,eddma,erosion,and small ulcers had the common features of UC.The common biopsy results were chro-nic inflammation and/or erosion.The average value of serum ALB decreases while the severity of UC patients increases.Drug thera-py was the main treatment of UC.The maintenance therapy was aminosalicylic acid,the effective ratio of treatment is 89.0%(55/73).Conclusion UC treatment plan basically follow the consensus and we should enhance the follow-up of UC patients.