CAJ | 학술논문

目的：探讨老年冠心病合并糖尿病患者的冠状动脉病变特征。方法选取经冠状动脉造影确诊为冠心病患者240例，年龄均＞60岁，其中合并糖尿病患者120例（糖尿病组），未合并糖尿病120例（非糖尿病组）。比较两组患者冠脉造影检查结果及临床资料、实验室检查结果的差异。结果两组患者性别、年龄、高血压病史、高脂血症病史、吸烟史以及总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇水平比较，差异无统计学意义（P＞0．05），糖尿病组冠状动脉三支病变发生率高于非糖尿病组（ P＜0．05），单支病变、两支／左主干病变发生率低于非糖尿病组（ P＜0．05）；与非糖尿病组相比，糖尿病组左回旋支、右冠状动脉狭窄比例更高（P＜0．05），冠状动脉病变支数更多、Gensini积分更高（P＜0．001）。结论老年冠心病合并糖尿病患者冠状动脉病变更广泛、更严重。
목적：탐토노년관심병합병당뇨병환자적관상동맥병변특정。방법선취경관상동맥조영학진위관심병환자240례，년령균＞60세，기중합병당뇨병환자120례（당뇨병조），미합병당뇨병120례（비당뇨병조）。비교량조환자관맥조영검사결과급림상자료、실험실검사결과적차이。결과량조환자성별、년령、고혈압병사、고지혈증병사、흡연사이급총담고순、감유삼지、저밀도지단백담고순、고밀도지단백담고순수평비교，차이무통계학의의（P＞0．05），당뇨병조관상동맥삼지병변발생솔고우비당뇨병조（ P＜0．05），단지병변、량지／좌주간병변발생솔저우비당뇨병조（ P＜0．05）；여비당뇨병조상비，당뇨병조좌회선지、우관상동맥협착비례경고（P＜0．05），관상동맥병변지수경다、Gensini적분경고（P＜0．001）。결론노년관심병합병당뇨병환자관상동맥병변경엄범、경엄중。
Objective To explore the clinical characteristics and features of coronary artery lesion in elderly patients with coronary heart disease( CHD) complicated with diabetes mellitus( DM) .Methods Two hundred and forty patients aged more than 60 years were diagnosed as CHD by coronary angiography and were enrolled in this study.There were 120 patients with DM( DM group) and 120 patients without DM( non-DM group) .The features of coronary artery lesions,clinical data and results of laboratory test were compared between two groups.Results There were no significant differences in gender,age,histories of high blood pressure,hyperlipemia and smoking,or the levels of total cholesterol, triglyceride, low density lipoprotein cholesterol and high density lipoprotein cholesterol between two groups (P>0.05).The incidence of three branches lesion of coronary artery was higher,but the incidence of single branch lesion or two branches/left main coronary artery lesion was lower in DM group compared with those in non-DM group (P<0.05).DM group gained higher proportions of narrow left circumflex coronary artery and narrow right coronary artery compared with non-DM group(P<0.05).The number of coronary artery lesions was more and the Gensini score was higher in DM group(P<0.001).Conclusion The coronary artery lesion is more extensive and severer in elderly patients with CHD complicated with DM.