CAJ | 학술논문

目的：探讨益母草注射液联合欣母沛(卡前列素氨丁三醇注射液)在阴道分娩产后出血中的应用价值。方法308例阴道分娩产妇,按照数字表法随机分为观察组和对照组,各154例。对照组采用腹壁宫体注射欣母沛预防产后出血,观察组采用腹壁宫体注射欣母沛和臀部肌内注射益母草注射液预防产后出血。计算产时,产后2、24 h的总出血量。产后3、7 d分别彩超测量子宫长径。结果对照组产后出血11例,发生率为7.1%；观察组产后出血4例,发生率为2.6%；两组比较,差异具有统计学意义(P<0.01)。对照组产时,产后2、24 h的总出血量分别为(143.4±29.4)、(237.8±34.2)、(296.3±36.2)ml；观察组分别为(71.2±17.3)、(136.2±25.6)、(172.7±31.1)ml,观察组均少于对照组(P<0.01)。对照组在产后3、7 d宫底高度分别为(16.4±1.3)、(14.7±1.2)cm；观察组分别为(13.1±1.1)、(10.4±0.8)cm；观察组均小于对照组(P<0.05)。结论益母草注射液联合欣母沛可以减少阴道分娩产妇的产后出血情况,利于子宫复旧,值得临床推广应用。
목적：탐토익모초주사액연합흔모패(잡전렬소안정삼순주사액)재음도분면산후출혈중적응용개치。방법308례음도분면산부,안조수자표법수궤분위관찰조화대조조,각154례。대조조채용복벽궁체주사흔모패예방산후출혈,관찰조채용복벽궁체주사흔모패화둔부기내주사익모초주사액예방산후출혈。계산산시,산후2、24 h적총출혈량。산후3、7 d분별채초측양자궁장경。결과대조조산후출혈11례,발생솔위7.1%；관찰조산후출혈4례,발생솔위2.6%；량조비교,차이구유통계학의의(P<0.01)。대조조산시,산후2、24 h적총출혈량분별위(143.4±29.4)、(237.8±34.2)、(296.3±36.2)ml；관찰조분별위(71.2±17.3)、(136.2±25.6)、(172.7±31.1)ml,관찰조균소우대조조(P<0.01)。대조조재산후3、7 d궁저고도분별위(16.4±1.3)、(14.7±1.2)cm；관찰조분별위(13.1±1.1)、(10.4±0.8)cm；관찰조균소우대조조(P<0.05)。결론익모초주사액연합흔모패가이감소음도분면산부적산후출혈정황,리우자궁복구,치득림상추엄응용。
ObjectiveTo investigate application value of leonurus injection combined with Hemabate (carboprost tromethamine injection) in postpartum hemorrhage of vaginal delivery.MethodsA total of 308 vaginal delivery puerpera were divided by random number table into observation group and control group, with 154 cases in each group. The control group received Hemabate injection in abdominal wall and uterus in prevention of hemorrhage, and the observation group received Hemabate injection in abdominal wall and uterus combined with Hip intramuscular injection of leonurus. Delivery time, and total bleeding volume in postpartum 2 and 24 h were calculated. Uterine length was detected by color Doppler ultrasound in postpartum 3 and 7 d.ResultsThere were 11 postpartum hemorrhage cases in the control group, with incidence as 7.1%. There were 4 postpartum hemorrhage cases in the observation group, with incidence as 2.6%. The difference between the two groups had statistical significance (P<0.01). The control group had total intrapartum and postpartum 2 and 24 h bleeding volume as (143.4±29.4), (237.8±34.2), (296.3±36.2) ml. Those in the observation group were respectively (71.2±17.3), (136.2±25.6), (172.7±31.1) ml. They were all lower in the observation group than in the control group (P<0.01). The control group had height of uterine fundus in postpartum 3 and 7 d as (16.4±1.3) and (14.7±1.2) cm. Those were respectively (13.1±1.1) and (10.4±0.8) cm in the observation group. The observation group had lower level than the control group (P<0.05).ConclusionImplement of leonurus injection combined with Hemabate can reduce postpartum hemorrhage of vaginal delivery. This method is beneficial for involution of uterus, and it is worthy of clinical promotion and application.