CAJ | 학술논문

目的：探讨肝细胞癌脑转移的临床特点及预后因素。方法回顾性分析1例肝细胞癌脑转移患者的临床资料，并结合相关文献对其临床特点及预后因素进行分析。结果本例患者以突发颅内出血急性起病，术前诊断颅内转移瘤。于全麻下行显微手术治疗，术后病理检查确诊为肝细胞癌脑转移。术后复查MRI显示颅内多发转移瘤，辅以全脑放射治疗，出院1个后随访尚良好存活。结论肝细胞癌脑转移发病率低，临床少见。尽管其预后极差，但包括外科手术在内的综合治疗能有效提高肝癌脑转移患者的生存质量，延长生存时间。对于肝细胞癌脑转移应高度警惕。
목적：탐토간세포암뇌전이적림상특점급예후인소。방법회고성분석1례간세포암뇌전이환자적림상자료，병결합상관문헌대기림상특점급예후인소진행분석。결과본례환자이돌발로내출혈급성기병，술전진단로내전이류。우전마하행현미수술치료，술후병리검사학진위간세포암뇌전이。술후복사MRI현시로내다발전이류，보이전뇌방사치료，출원1개후수방상량호존활。결론간세포암뇌전이발병솔저，림상소견。진관기예후겁차，단포괄외과수술재내적종합치료능유효제고간암뇌전이환자적생존질량，연장생존시간。대우간세포암뇌전이응고도경척。
Objective To explore the clinical characteristics and prognostic factors of the brain metastases (BM) of hepatocellular carcinoma ( HCC).Methods The clinical data of a patient with BM of HCC was analyzed retrospectively .The clinical characteristics and prognostic factors were analyzed based on the related literature review.Results The patient was admitted in our hospital for intracranial hemorrhage and was diagnosed as BM before operation .He underwent microsurgery under general anesthesia , and diagnosed as BM of HCC by postoperative pathologic examination . The MRI was checked after operation which showed multiple intracranial metastatic neoplasms.The whole-brain radiation therapy (WBRT) was followed.The patient was survived well during the One month follow-up after hospital discharge .Conclusion BM from HCC is very rare and has a low morbidity .Although patients with it are associated with a very poor prognosis , comprehensive treatment including surgical resection may improve the life quality and prolong survival time .The diagnosis of BM from HCC should be on high alert , particularly in HCC high morbidity areas such as china .