CAJ | 학술논문

目的观察中医序贯疗法治疗急性鼻-鼻窦炎的临床疗效.方法 108例肺经风热型急性鼻-鼻窦炎、慢性鼻-鼻窦炎急性发作患者按照随机数字表法随机分为3组各36例,序贯疗法组采用煎药蒸气熏蒸鼻窍并口服治疗,连续用药1周,再单纯用煎药蒸气熏蒸鼻窍,连续1周;口服汤药组:采用与序贯疗法组相同的煎药口服2周;口服西药组:口服阿莫西林克拉维酸钾片,连续服用2周.分别于治疗前后观察并记录各组患者的鼻塞、流涕、鼻黏膜充血肿胀程度、头痛、嗅觉障碍、局部压痛的积分及病情程度视觉模拟量表、鼻塞视觉模拟量表积分.结果序贯疗法组、口服汤药组、口服西药组的总有效率分别为91.7%、84.4%、86.2%,差异无统计学意义(P>0.05).2组的痊愈、显效、有效、无效的疗效等级比较差异有统计学意义(χ2=10.660,P=0.010).治疗第 14 天,鼻塞积分、鼻黏膜充血肿胀程度积分、鼻塞视觉模拟量表积分、总积分,序贯疗法组[分别为(0.39±0.80)分、(1.44±1.83)分、(0.62±1.55)分、(3.94±3.26)分],与口服汤药组[分别为(0.94±1.24)分、(2.44±2.02)分、(1.28±1.44)分、(6.94±5.54)分]、口服西药组[分别为(1.10±1.15)分、(3.24±1.96)分、(1.59±2.15)分、(7.10±4.06)分]比较,差异有统计学意义(P<0.05).结论中医序贯疗法治疗急性鼻-鼻窦炎、、慢性鼻-鼻窦炎急性发作疗效显著,且安全无明显不良反应.
목적 관찰중의서관요법치료급성비-비두염적림상료효.방법 108례폐경풍열형급성비-비두염、만성비-비두염급성발작환자안조수궤수자표법수궤분위3조각36례,서관요법조채용전약증기훈증비규병구복치료,련속용약1주,재단순용전약증기훈증비규,련속1주;구복탕약조:채용여서관요법조상동적전약구복2주;구복서약조:구복아막서림극랍유산갑편,련속복용2주.분별우치료전후관찰병기록각조환자적비새、류체、비점막충혈종창정도、두통、후각장애、국부압통적적분급병정정도시각모의량표、비새시각모의량표적분.결과 서관요법조、구복탕약조、구복서약조적총유효솔분별위91.7%、84.4%、86.2%,차이무통계학의의(P>0.05).2조적전유、현효、유효、무효적료효등급비교차이유통계학의의(χ2=10.660,P=0.010).치료제 14 천,비새적분、비점막충혈종창정도적분、비새시각모의량표적분、총적분,서관요법조[분별위(0.39±0.80)분、(1.44±1.83)분、(0.62±1.55)분、(3.94±3.26)분],여구복탕약조[분별위(0.94±1.24)분、(2.44±2.02)분、(1.28±1.44)분、(6.94±5.54)분]、구복서약조[분별위(1.10±1.15)분、(3.24±1.96)분、(1.59±2.15)분、(7.10±4.06)분]비교,차이유통계학의의(P<0.05).결론 중의서관요법치료급성비-비두염、、만성비-비두염급성발작료효현저,차안전무명현불량반응.
Objective To assess the clinical eficacy of TCM sequential therapy treatment of acute rhinosinusitis.Methods 108 acute rhinosinusitis of the Lung Channel with wind-heat type patients were divided into three groups according to random digits table: sequential therapy group, traditional Chinese medicine group, and western medicine group. On day 0, day 7, day 14, recorded the date of nasal obstruction, running nose, nasal mucosa congestion degree of swelling, headache, smell disorders, local tenderness points , the severity of the disease visual analogue scale, nasal obstruction visual analogue scale. We regarded 2 weeks as a course of treatment.Results The total efficiency was 91.67% in the sequential therapy group, 84.37% in the traditional Chinese medicine, 86.21% in the western medicine group, with no significant difference (P>0.05). There was a significant difference in efficacy level of the total recovery, obvious efficiency, efficiency and no efficiency (P<0.05). In the date of nasal obstruction, nasal mucosa congestion degree of swelling, nasal  obstruction visual analogue scale and the total score, the sequential therapy group (0.39±0.80), (1.44±1.83), (0.62±1.55),(3.94±3.26)respectively, was significantly improved than the Chinese medicine group (0.94± 1.24), (2.44±2.02), (1.28±1.44), (6.94±5.54)respectively, and the western medicine group (1.10±1.15), (3.24±1.96), (1.59±2.15),(7.10±4.06) respectively on 14 day(P<0.05).Conclusion The curative effect of sequential therapy of traditional Chinese medicine in the treatment of acute rhinosinusitis is distinct and safe.