中国综合临床
中國綜閤臨床
중국종합림상
Clinical Medicine of China
2015年
9期
849-851
,共3页
米索前列醇%计划分娩%妊娠结局%宫颈成熟
米索前列醇%計劃分娩%妊娠結跼%宮頸成熟
미색전렬순%계화분면%임신결국%궁경성숙
Misoprostol%Planned delivery%Outcomes of pregnancy%Cervical ripening
目的 探讨颊黏膜含化米索前列醇在足月妊娠计划分娩中促进宫颈成熟的临床效果,以及对妊娠结局和新生儿出生情况的影响.方法 96例宫颈Bishop评分≤4分的初产妇按照随机原则分为对照组和研究组,每组48例.对照组产妇分娩前使用缩宫素,研究组产妇接受颊黏膜含化米索前列醇促进宫颈成熟.比较两组产妇促宫颈成熟度效果、引产效果、妊娠结局和新生儿出生情况的差异.结果 研究组产妇促宫颈成熟度总有效率91.7％(44/48)明显高于对照组66.7％ (32/48),差异有统计学意义(x2=7.834,P＝0.015).研究组产妇引产总有效率93.8％ (45/48)明显高于对照组54.2％(26/48),差异有统计学意义(x2=9.653,P=0.004).研究组与对照组产妇产后出血量[(183.6±24.2) ml与(216.5±32.6) ml,t=6.748]、总产程[(7.6±1.3)h与(11.3±2.5)h,t=6.636]和剖宫产率[31.3％(15/48)与47.9％ (23/48),x2=5.637]比较,研究组均明显低于对照组,差异均有统计学意义(P均＜0.05).两组产妇娩出的新生儿羊水污染和新生儿窒息发生率差异均无统计学意义(P均＞0.05).结论 颊黏膜含化米索前列醇促宫颈成熟效果明显,对母婴影响小,用于计划分娩安全有效.
目的 探討頰黏膜含化米索前列醇在足月妊娠計劃分娩中促進宮頸成熟的臨床效果,以及對妊娠結跼和新生兒齣生情況的影響.方法 96例宮頸Bishop評分≤4分的初產婦按照隨機原則分為對照組和研究組,每組48例.對照組產婦分娩前使用縮宮素,研究組產婦接受頰黏膜含化米索前列醇促進宮頸成熟.比較兩組產婦促宮頸成熟度效果、引產效果、妊娠結跼和新生兒齣生情況的差異.結果 研究組產婦促宮頸成熟度總有效率91.7％(44/48)明顯高于對照組66.7％ (32/48),差異有統計學意義(x2=7.834,P＝0.015).研究組產婦引產總有效率93.8％ (45/48)明顯高于對照組54.2％(26/48),差異有統計學意義(x2=9.653,P=0.004).研究組與對照組產婦產後齣血量[(183.6±24.2) ml與(216.5±32.6) ml,t=6.748]、總產程[(7.6±1.3)h與(11.3±2.5)h,t=6.636]和剖宮產率[31.3％(15/48)與47.9％ (23/48),x2=5.637]比較,研究組均明顯低于對照組,差異均有統計學意義(P均＜0.05).兩組產婦娩齣的新生兒羊水汙染和新生兒窒息髮生率差異均無統計學意義(P均＞0.05).結論 頰黏膜含化米索前列醇促宮頸成熟效果明顯,對母嬰影響小,用于計劃分娩安全有效.
목적 탐토협점막함화미색전렬순재족월임신계화분면중촉진궁경성숙적림상효과,이급대임신결국화신생인출생정황적영향.방법 96례궁경Bishop평분≤4분적초산부안조수궤원칙분위대조조화연구조,매조48례.대조조산부분면전사용축궁소,연구조산부접수협점막함화미색전렬순촉진궁경성숙.비교량조산부촉궁경성숙도효과、인산효과、임신결국화신생인출생정황적차이.결과 연구조산부촉궁경성숙도총유효솔91.7％(44/48)명현고우대조조66.7％ (32/48),차이유통계학의의(x2=7.834,P＝0.015).연구조산부인산총유효솔93.8％ (45/48)명현고우대조조54.2％(26/48),차이유통계학의의(x2=9.653,P=0.004).연구조여대조조산부산후출혈량[(183.6±24.2) ml여(216.5±32.6) ml,t=6.748]、총산정[(7.6±1.3)h여(11.3±2.5)h,t=6.636]화부궁산솔[31.3％(15/48)여47.9％ (23/48),x2=5.637]비교,연구조균명현저우대조조,차이균유통계학의의(P균＜0.05).량조산부면출적신생인양수오염화신생인질식발생솔차이균무통계학의의(P균＞0.05).결론 협점막함화미색전렬순촉궁경성숙효과명현,대모영영향소,용우계화분면안전유효.
Objective To discuss the clinical effect of sublingual misoprostol on planned delivery with full-term pregnancy and influence on outcomes of pregnancy and newborns.Methods Ninety-six puerpera with cervical bishop score ≤ 4 were randomly divided into the control group(n =48) and research group (n =48).The patients of the control group were given oxytocin therapy while the research group were given sublingual misoprostol.The promoting effect of cervical maturity,induced abortion effects,outcomes of pregnancy and newborns between the two groups were compared.Results The total effective rate of cervical maturity of research group was obviously higher than that of control group,the differences were statistically significant (91.7％ (44/48) vs 66.7％ (32/48),x2=7.834,P =0.015).The total effective rate of induced abortion effects of research group was obviously higher than that of control group,the differences were statistically significant (93.8％ (45/48) vs 54.2％ (26/48),x2=9.653,P=0.004).The postpartum hemorrhage((183.6±24.2) ml vs.(216.5±32.6) ml,t=6.748),total stageoflabor((7.6±1.3) h vs.(11.3±2.5) h,t=6.636) and cesarean section rate(31.3％ vs.47.9％,x2 =5.637) of research group was obviously lower than that of control group,the differences were statistically significant (P＜0.05).Two groups of newborns and the incidence of neonatal asphyxia,amniotic fluid pollution had no statistically significant difference(P＞0.05).Conclusion The clinical effect of sublingual misoprostol on.planned delivery with full-term pregnancy is obvious and causes little influence on outcomes of pregnancy and newborns.It is safe and effective to be applied on planned delivery and worth popularization and application.
