CAJ | 학술논문

人参皂苷（GS）为人参的主要成分，包括 Rg3、Rh2、Rd、Rh1、Rg2等数十种单体。GS 及其各种单体抗肝癌机制各异，主要机制包括以下方面：诱导肝癌细胞凋亡、抑制肝癌细胞增殖、抑制肝癌细胞侵袭和转移、逆转肝癌细胞多药耐药、联合其他治疗手段的协同增效作用、提高机体免疫功能、抑制肝脏葡萄糖生成。不同的 GS 单体通过各自途径发挥不同的抗肝癌作用。
인삼조감（GS）위인삼적주요성분，포괄 Rg3、Rh2、Rd、Rh1、Rg2등수십충단체。GS 급기각충단체항간암궤제각이，주요궤제포괄이하방면：유도간암세포조망、억제간암세포증식、억제간암세포침습화전이、역전간암세포다약내약、연합기타치료수단적협동증효작용、제고궤체면역공능、억제간장포도당생성。불동적 GS 단체통과각자도경발휘불동적항간암작용。
Ginsenosides (GS)as the main ingredient of ginseng,include dozens of monomer,such as Rg3,Rh2,Rd,Rh1 ,Rg2,etc.GS and various monomers have different anti-hepatoma mechanisms.The main mechanism includes the following aspects,inducing the apoptosis of liver cancer cells,inhibiting the prolifera-tion,invasion and metastasis,reversing the multidrug resistance of liver cancer cells,increasing therapeutic effects by combining with other treatments,improving the immune function of organism and inhibiting hepatic glu-cose production.Different GS monomers play different roles of anti-hepatoma through their respective channels.