CAJ | 학술논문

微小 RNA（miRNA）通过对目的基因翻译的调节，在肝癌复发的各机制中起重要作用。研究显示 miRNA 的异常表达与肝癌的复发密切相关，机制包括调控肿瘤血管生成和肿瘤细胞增殖等。miRNA 可能成为最具潜力的肝癌治疗靶点，并在复发预测方面具有独特优势。
미소 RNA（miRNA）통과대목적기인번역적조절，재간암복발적각궤제중기중요작용。연구현시 miRNA 적이상표체여간암적복발밀절상관，궤제포괄조공종류혈관생성화종류세포증식등。miRNA 가능성위최구잠력적간암치료파점，병재복발예측방면구유독특우세。
microRNAs (miRNAs)play important roles in recurrent hepatocellular carcinoma by regula-ting translation of target gene expression.Researches show that the abnormal expressions of miRNAs are closely related to the recurrent hepatocellular carcinoma,and the mechanisms include regulation of tumor angiogenesis and proliferation of tumor cells.miRNAs may be the most potential therapeutic targets for recurrent hepatocellu-lar carcinoma and have special advantages in prediction.