湖南中医药大学学报
湖南中醫藥大學學報
호남중의약대학학보
Journal of Traditional Chinese Medicine University of Hunan
2015年
9期
58-61
,共4页
刘百祥%肖旭平%严文辉%叶剑荣%肖瑶%张旻昱%周建波%邓坦%刘劲
劉百祥%肖旭平%嚴文輝%葉劍榮%肖瑤%張旻昱%週建波%鄧坦%劉勁
류백상%초욱평%엄문휘%협검영%초요%장민욱%주건파%산탄%류경
鼻咽癌%放疗%薯蓣丸加减方%EB病毒%薯蓣%生地黄%天花粉
鼻嚥癌%放療%藷蕷汍加減方%EB病毒%藷蕷%生地黃%天花粉
비인암%방료%서여환가감방%EB병독%서여%생지황%천화분
nasopharyngeal carcinoma%modified Dioscorea Pills prescription%EB virus%dioscorea%fresh rehmannia%Mongolian snakegourd root
目的 观察薯蓣丸加减方对鼻咽癌放疗患者EB病毒的影响. 方法 将60例鼻咽癌患者随机分为观察组和对照组各30例,观察组在放疗开始第1天给予口服薯蓣丸加减方治疗,对照组在开始放疗第1天给予康复新液治疗. 观察两组治疗前后临床疗效、 患者生活质量及EB病毒DNA水平. 结果 治疗后观察组临床疗效及中医症候疗效均优于对照组 (P<0.05);两组生活质量均有明显改善(P<0.05),观察组改善更为显著(P<0.01);血浆EBV-DNA水平均较治疗前下降(P<0.05),观察组下降更为显著(P<0.01). 结论 薯蓣丸加减方对鼻咽癌放疗患者有较好的治疗作用,可提高患者生活质量,其作用机制可能与降低鼻咽癌患者血浆EBV-DNA水平有关.
目的 觀察藷蕷汍加減方對鼻嚥癌放療患者EB病毒的影響. 方法 將60例鼻嚥癌患者隨機分為觀察組和對照組各30例,觀察組在放療開始第1天給予口服藷蕷汍加減方治療,對照組在開始放療第1天給予康複新液治療. 觀察兩組治療前後臨床療效、 患者生活質量及EB病毒DNA水平. 結果 治療後觀察組臨床療效及中醫癥候療效均優于對照組 (P<0.05);兩組生活質量均有明顯改善(P<0.05),觀察組改善更為顯著(P<0.01);血漿EBV-DNA水平均較治療前下降(P<0.05),觀察組下降更為顯著(P<0.01). 結論 藷蕷汍加減方對鼻嚥癌放療患者有較好的治療作用,可提高患者生活質量,其作用機製可能與降低鼻嚥癌患者血漿EBV-DNA水平有關.
목적 관찰서여환가감방대비인암방료환자EB병독적영향. 방법 장60례비인암환자수궤분위관찰조화대조조각30례,관찰조재방료개시제1천급여구복서여환가감방치료,대조조재개시방료제1천급여강복신액치료. 관찰량조치료전후림상료효、 환자생활질량급EB병독DNA수평. 결과 치료후관찰조림상료효급중의증후료효균우우대조조 (P<0.05);량조생활질량균유명현개선(P<0.05),관찰조개선경위현저(P<0.01);혈장EBV-DNA수평균교치료전하강(P<0.05),관찰조하강경위현저(P<0.01). 결론 서여환가감방대비인암방료환자유교호적치료작용,가제고환자생활질량,기작용궤제가능여강저비인암환자혈장EBV-DNA수평유관.
Objective To observe the effect of modified Dioscorea Pills prescription on EB virus in nasopharyngeal carcinoma patients receiving radiotherapy. Methods 60 cases of patients with nasopharyngeal carcinoma (NPC) were randomly divided into the observation group and the control group, 30 cases in each group. The observation group was given modified Dioscorea Pills prescription for treatment on the first day receiving radiotherapy, the control group was given Kangfuxin on the first day. The clinical curative effect, quality of life and EB virus DNA levels in two groups were observed before and after treatment. Results After treatment, the clinical curative effect and TCM syndrome efficacy of observed group were better than control group (P<0.05); The level of the quality of life in the two groups was improved obviously (P<0.05); The improvement in observation group was more significant (P<0.01). The plasma EBV-DNA levels of two groups were lower than before (P<0.05), the observation group decreased significantly (P<0.01). Conclusion Modified Dioscorea Pills prescription show good effect in treatment of patients with NPC and can improve the quality of life of patients, and its mechanism may be associated with the decrease of plasma EBV-DNA levels.
