脑与神经疾病杂志
腦與神經疾病雜誌
뇌여신경질병잡지
Journal of Brain and Nervous Diseases
2015年
5期
329-331
,共3页
脑出血%深静脉血栓形成%同型半胱氨酸%抗凝治疗
腦齣血%深靜脈血栓形成%同型半胱氨痠%抗凝治療
뇌출혈%심정맥혈전형성%동형반광안산%항응치료
Cerebral hemorrhage%Deep veinthrombosis%Homocysteine%Anticoagulation
目的探讨脑出血患者下肢深静脉血栓形成的相关因素。方法收集2007年1月至2010年12月214例脑出血患者住院临床资料，通过单因素分析及多因素Logistic回归分析确定脑出血患者并发下肢深静脉血栓形成的独立危险因素。结果单因素分析发现格拉斯哥昏迷评分、出血部位、出血量及血浆同型半胱氨酸水平与脑出血患者下肢深静脉血栓形成相关（P＜0．05），性别、年龄、高血压、糖尿病、高脂血症、吸烟、饮酒、D-二聚体、凝血酶原时间、活化部分凝血活酶时间及血小板计数与深静脉血栓形成无关（ P＞0．05）。多因素分析进一步证实出血部位、出血量及血浆同型半胱氨酸水平是影响脑出血患者下肢深静脉血栓形成的独立因素（ P＜0．05）。结论出血部位、出血量及血浆同型半胱氨酸水平是影响脑出血患者下肢深静脉血栓形成的独立危险因素，可以作为预防性抗凝治疗的参考指标。
目的探討腦齣血患者下肢深靜脈血栓形成的相關因素。方法收集2007年1月至2010年12月214例腦齣血患者住院臨床資料，通過單因素分析及多因素Logistic迴歸分析確定腦齣血患者併髮下肢深靜脈血栓形成的獨立危險因素。結果單因素分析髮現格拉斯哥昏迷評分、齣血部位、齣血量及血漿同型半胱氨痠水平與腦齣血患者下肢深靜脈血栓形成相關（P＜0．05），性彆、年齡、高血壓、糖尿病、高脂血癥、吸煙、飲酒、D-二聚體、凝血酶原時間、活化部分凝血活酶時間及血小闆計數與深靜脈血栓形成無關（ P＞0．05）。多因素分析進一步證實齣血部位、齣血量及血漿同型半胱氨痠水平是影響腦齣血患者下肢深靜脈血栓形成的獨立因素（ P＜0．05）。結論齣血部位、齣血量及血漿同型半胱氨痠水平是影響腦齣血患者下肢深靜脈血栓形成的獨立危險因素，可以作為預防性抗凝治療的參攷指標。
목적탐토뇌출혈환자하지심정맥혈전형성적상관인소。방법수집2007년1월지2010년12월214례뇌출혈환자주원림상자료，통과단인소분석급다인소Logistic회귀분석학정뇌출혈환자병발하지심정맥혈전형성적독립위험인소。결과단인소분석발현격랍사가혼미평분、출혈부위、출혈량급혈장동형반광안산수평여뇌출혈환자하지심정맥혈전형성상관（P＜0．05），성별、년령、고혈압、당뇨병、고지혈증、흡연、음주、D-이취체、응혈매원시간、활화부분응혈활매시간급혈소판계수여심정맥혈전형성무관（ P＞0．05）。다인소분석진일보증실출혈부위、출혈량급혈장동형반광안산수평시영향뇌출혈환자하지심정맥혈전형성적독립인소（ P＜0．05）。결론출혈부위、출혈량급혈장동형반광안산수평시영향뇌출혈환자하지심정맥혈전형성적독립위험인소，가이작위예방성항응치료적삼고지표。
Objective To explore the factors related with thrombosis in deep vein of low limbers in patients suffering from cerebral hemorrhage .Methods The clinic data of 214 cases with cerebral hemorrhage collected from January 2007 to December 2010 were analyzed retrospectively by univariate analysis and multivariate Logistic regression,and the independent risk factors will be found .Results The Glasgow Coma Scale score ,the location and volume of cerebral hemorrhage and homocysteine were related with thrombosis in deep vein of low limbers in patients with cerebral hemorrhage in univariate analysis ( P<0.05 );and they were also the independent risk factors of thrombosis in deep vein of low limbers except Glasgow Coma Scale score in multivariate Logistic regression (P<0.05);the gender, age, hypertension or not, diabetes mellitus or not, hyperlipoidemia, smoking, drinking, d-dimer, prothrombin time, activated partial thromboplastin time and platelet count had no relation with thrombosis in deep vein of low limbers ( P>0.05) .Conclusion The location and volume of cerebral hemorrhage and homocysteine are the independent risk factors leading to thrombosis in deep vein of low limbers in patients with cerebral hemorrhage ,and they can be important indices for prophylactic anticoagulation in this kind of cases .
