中国综合临床
中國綜閤臨床
중국종합림상
Clinical Medicine of China
2015年
9期
852-855
,共4页
围绝经期综合征%激素补充%中西医综合治疗
圍絕經期綜閤徵%激素補充%中西醫綜閤治療
위절경기종합정%격소보충%중서의종합치료
Peri-menopausal syndrome%Hormone replacement%Integrated traditional Chinese and Western medicine treatment
目的 探讨中重度围绝经期综合征的的有效治疗方法,提高围绝经期及绝经后妇女的生活质量.方法 回顾性分析216例确诊为中重度围绝经期综合征患者的临床资料.单纯激素补充治疗(HT)组60例,单纯中医药治疗组90例,激素补充和中医药综合治疗组66例.于治疗3个月后随访症状改善和不良反应情况.结果 3组治疗3个月后患者的临床症状均有不同程度改善,单纯激素补充治疗、单纯中医药治疗、激素补充和中医药综合治疗组总有效率分别为90％ (54/60)、82％ (76/90)、100％(66/66),3组比较,差异均具有统计学意义(x2=13.160,P＜0.01).单纯激素补充治疗、单纯中医药治疗、激素补充和中医药综合治疗组治疗3个月不良反应分别为27例(45％)、1例(1％)、4例(6％),差异有统计学意义(x2=60.720,P＜0.01),中医药治疗组、综合治疗组不良反应发生率高于单纯激素治疗组,差异有统计学意义(P均＜0.01),中医药治疗组和综合治疗组比较,差异无统计学意义(P＞0.05).结论 在治疗中重度围绝经期综合征时,对于有激素补充治疗适应证无禁忌证者,建议采取中西医综合治疗,对有激素补充禁忌证或不愿意激素补充治疗者,中医药治疗也有不错的效果.
目的 探討中重度圍絕經期綜閤徵的的有效治療方法,提高圍絕經期及絕經後婦女的生活質量.方法 迴顧性分析216例確診為中重度圍絕經期綜閤徵患者的臨床資料.單純激素補充治療(HT)組60例,單純中醫藥治療組90例,激素補充和中醫藥綜閤治療組66例.于治療3箇月後隨訪癥狀改善和不良反應情況.結果 3組治療3箇月後患者的臨床癥狀均有不同程度改善,單純激素補充治療、單純中醫藥治療、激素補充和中醫藥綜閤治療組總有效率分彆為90％ (54/60)、82％ (76/90)、100％(66/66),3組比較,差異均具有統計學意義(x2=13.160,P＜0.01).單純激素補充治療、單純中醫藥治療、激素補充和中醫藥綜閤治療組治療3箇月不良反應分彆為27例(45％)、1例(1％)、4例(6％),差異有統計學意義(x2=60.720,P＜0.01),中醫藥治療組、綜閤治療組不良反應髮生率高于單純激素治療組,差異有統計學意義(P均＜0.01),中醫藥治療組和綜閤治療組比較,差異無統計學意義(P＞0.05).結論 在治療中重度圍絕經期綜閤徵時,對于有激素補充治療適應證無禁忌證者,建議採取中西醫綜閤治療,對有激素補充禁忌證或不願意激素補充治療者,中醫藥治療也有不錯的效果.
목적 탐토중중도위절경기종합정적적유효치료방법,제고위절경기급절경후부녀적생활질량.방법 회고성분석216례학진위중중도위절경기종합정환자적림상자료.단순격소보충치료(HT)조60례,단순중의약치료조90례,격소보충화중의약종합치료조66례.우치료3개월후수방증상개선화불량반응정황.결과 3조치료3개월후환자적림상증상균유불동정도개선,단순격소보충치료、단순중의약치료、격소보충화중의약종합치료조총유효솔분별위90％ (54/60)、82％ (76/90)、100％(66/66),3조비교,차이균구유통계학의의(x2=13.160,P＜0.01).단순격소보충치료、단순중의약치료、격소보충화중의약종합치료조치료3개월불량반응분별위27례(45％)、1례(1％)、4례(6％),차이유통계학의의(x2=60.720,P＜0.01),중의약치료조、종합치료조불량반응발생솔고우단순격소치료조,차이유통계학의의(P균＜0.01),중의약치료조화종합치료조비교,차이무통계학의의(P＞0.05).결론 재치료중중도위절경기종합정시,대우유격소보충치료괄응증무금기증자,건의채취중서의종합치료,대유격소보충금기증혹불원의격소보충치료자,중의약치료야유불착적효과.
Objective To observe the effective treatment of severe in peri-menopausal syndrome,and improve the quality of life of women in perimenopausall and postmenopausal women.Methods We review the different treatment methods in the 216 patients diagnosed with moderate to severe menopausal syndrome.Group A:simple hormone replacement therapy (HT) of 60 cases.Group B:simple treatment of traditional Chinese medicine of 90 cases.Group C:hormone replacement and comprehensive therapy of Chinese medicine of 66 cases.Follow up the improvement of symptoms and adverse reactions after the treatment one and three month respectively.Results The three groups after treatment in patients with clinical symptoms were improved after three month.Efficient comparisons among third group,the differences were statistically significant (90％ (54/60),82％ (76/90),100％ (66/66);x2 =13.160,P ＜ 0.01).Adverse reactions of 3 treatment group comparison difference had statistical significance (45％ (27/60,1％ (1/90),6％ (4/66);x2 =60.720,P ＜0.01).Compared with pure hormone treatment group,treatment group of Chinese medicine,comprehensive treatment group adverse reactions happen was less,the difference was statistically significant(P＜0.01).Chinese medicine treatment group and combined treatment group,there was no statistically significant difference (P ＞0.05).Conclusion Severe menopausal syndrome with hormone replacement therapy indications without contraindications suggestions take comprehensive treatment of traditional Chinese and Western medicine,The hormone supplement contraindications or unwilling to hormone replacement therapy,also has good effect of Chinese medicine treating.
