CAJ | 학술논문

目的系统综述国内外老年糖尿病共患抑郁障碍的流行病学资料、危险因素、可能机制、治疗干预等,为今后该病的早期诊断、病情评估、治疗提供新思路.方法通过系统检索CBM、CNKI、VIP、万方、PubMed、EMBASE、Cochrane图书馆,纳入2000～2015年有关老年糖尿病共患抑郁障碍的文献41篇.结果老年糖尿病共患抑郁障碍的发病率高,症状不典型,病理机制复杂,较少引起患者和医务人员的重视,对患者的预后影响大,早期预防和治疗有效.结论老年糖尿病和抑郁常共病,两者对预后有负性协同效应,已引起人们重视.但有关二者的回顾性调查研究较多,前瞻性研究较少,尤其是随机双盲对照研究更少,应进一步从多角度加强该病的研究,从而提高该病的病因、诊断、治疗、预后水平.
목적 계통종술국내외노년당뇨병공환억욱장애적류행병학자료、위험인소、가능궤제、치료간예등,위금후해병적조기진단、병정평고、치료제공신사로.방법 통과계통검색CBM、CNKI、VIP、만방、PubMed、EMBASE、Cochrane도서관,납입2000～2015년유관노년당뇨병공환억욱장애적문헌41편.결과 노년당뇨병공환억욱장애적발병솔고,증상불전형,병리궤제복잡,교소인기환자화의무인원적중시,대환자적예후영향대,조기예방화치료유효.결론 노년당뇨병화억욱상공병,량자대예후유부성협동효응,이인기인문중시.단유관이자적회고성조사연구교다,전첨성연구교소,우기시수궤쌍맹대조연구경소,응진일보종다각도가강해병적연구,종이제고해병적병인、진단、치료、예후수평.
Objective Systematic review of the epidemiology,risk factors,possible mechanisms and treatment of the depression among older adults with diabetes mellitus,and to provide new ideas for the early diagnosis,evaluation and treatment of the disease in the future.Methods Forty-one studies from 2000 to 2015 were identified manualy and online by using CBM,CNKI,VIP,Wanfang databases,PubMed,EMBASE and the Cochrane library.Results Among older adults with DM,depression was highly prevalent,and their clinical manifestations were not typical.The mechanisms of depression was not entirely clear and it less likely to cause the attention of patients and medical staff and it seriously affected the prognosis of diabetic patients.Early prevention and treatment were effective.Conclusion Diabetes mellitus and depression are frequently comorbid in older adult patients.Considering the negative synergistic effects on the health outcomes resulted by comorbid depression and DM.There are a lot of researches about the two disease's retrospective study,but the prospective study is less,especially the ran-domized double blind controlled study.Further study should be strengthened to improve the etiology,diagnosis,treatment and prognosis of the disease.